Results 61 to 70 of about 2,845,265 (325)

Intravoxel incoherent motion DWI of the pancreatic adenocarcinomas: monoexponential and biexponential apparent diffusion parameters and histopathological correlations

Cancer Imaging, 2017
Background To investigate the associations between the diffusion parameters obtained from multiple-b-values diffusion weighted imaging (DWI) of pancreatic ductal adenocarcinoma (PDAC) and the aggressiveness and local stage prediction, and assess the ...
Chao Ma, Yanjun Li, Li Wang, Yang Wang, Yong Zhang, He Wang, Shiyue Chen, Jianping Lu   +7 more
doaj   +1 more source

Relevance of diffusion-weighted imaging with background body signal suppression for staging, prognosis, morphology, treatment response, and apparent diffusion coefficient in plasma-cell neoplasms: A single-center, retrospective study.

PLoS ONE, 2021
Accurate staging and evaluation of therapeutic effects are important in managing plasma-cell neoplasms. Diffusion-weighted imaging with body signal suppression magnetic resonance imaging (DWIBS-MRI) allows for acquisition of whole-body volumetric data ...
Akiko Yamada, Yoichi Araki, Yuko Tanaka, Shunsuke Otsuki, Arisa Yamada, Mitsuru Moriyama, Seiichiro Katagiri, Tamiko Suguro, Michiyo Asano, Seiichiro Yoshizawa, Daigo Akahane, Nahoko Furuya, Hiroaki Fujimoto, Seiichi Okabe, Moritaka Gotoh, Kunihito Suzuki, Kazuhiro Saito, Akihiko Gotoh   +17 more
doaj   +1 more source

Role of Apparent Diffusion Coefficient in evaluation of rectal cancer aggressiveness [PDF]

Zagazig University Medical Journal, 2020
Objectives: To evaluate the importance of diffusion-weighted MRI imaging (DWI) as a truthful marker for detection of rectal cancer tumor aggressiveness, by studying the relation between apparent diffusion coefficient (ADC) values of the tumors, MRI ...
Mona Refaat, Mostafa Assy, ahmed salem
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Receiver-operating characteristic (ROC) curve for median apparent diffusion coefficient.

, 2023
Receiver-operating characteristic (ROC) curve for median apparent diffusion coefficient.
Takahiro Sueoka (14992628), Saki Kawai (14992631), Tatsuo Ichinohe (3571925), Takakazu Kawase (341461), Kazuo Awai (515602), Nobuko Tanitame (14992634), Ryo Higashino (14992625), Miyuki Takasu (515596), Akihisa Tamura (14992637), Makoto Iida (3586817)   +9 more
core   +1 more source

Apparent Diffusion Coefficient in Predicting the Preoperative Grade of Meningiomas

Journal of the College of Physicians and Surgeons Pakistan, 2020
To investigate the relationship between the apparent diffusion coefficients (ADC) value obtained from magnetic resonance imaging (MRI) and histopathologic grade of meningiomas.Observational study.Department of Radiology, Istanbul Medeniyet University, School of Medicine, Istanbul, Turkey between January 2015 and June 2019.Data of 45 patients with ...
Basak, Atalay, Suna Sahin, Ediz, Nurver Ozel, Ozbay   +2 more
openaire   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

ICACE-Chloride-Diffusion-Coefficient-Paper.pdf

, 2019
Predicting service life is an essential aspect of long-term sustainability of any reinforced concrete (RC) infrastructure in a marine environment. The service life of RC is primarily affected by chloride induced corrosion of embedded reinforcement and ...
Naqib Mashrur (6419105)
core   +1 more source

Prognostic Value of Apparent Diffusion Coefficient (ADC) in Patients with Diffuse Gliomas [PDF]

Cancers
This study aimed to evaluate potential posttreatment changes in ADC values within the tissue surrounding the enhancing lesion, particularly in areas not exhibiting MRI characteristics of involvement. Additionally, the objective was to investigate the correlations among ADC values, treatment response, and survival outcomes in individuals diagnosed with ...
Marija Bušić, Zoran Rumboldt, Dora Čerina, Željko Bušić, Krešimir Dolić   +4 more
openaire   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source