Results 61 to 70 of about 3,053,893 (297)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

The role of multiparametric magnetic resonance imaging in the differentiation of low- and high-grade non-muscle invasive bladder cancer

Diagnostic and Interventional Radiology
PURPOSE: To evaluate the diagnostic efficacy of apparent diffusion coefficient (ADC) measurements and semiquantitative dynamic contrast enhancement (DCE) parameters in predicting the differentiation between low- and high-grade tumors in non-muscle ...
Merve Nur Taşdemir, Uluhan Eryürük, Ural Oğuz, Birgül Tok, Serdar Aslan   +4 more
doaj   +1 more source

Evaluation of Correlation of Ki-67 Factor in Prostate Cancer with Apparent Diffusion Coefficient Index in Multi b-value Diffusion Magnetic Resonance Imaging

مجله دانشکده پزشکی اصفهان, 2020
Background: Recent advances in molecular imaging of prostate cancer, including diffusion-weighted imaging, have led to improved cancer screening methods.
Mehdi Akbari, Mohammad Bagher Tavakoli, Mohammadhoseyn Izadpanahi, Iraj Abedi, Saied Khanbabapour   +4 more
doaj   +1 more source

Predictors of Apparent Diffusion Coefficient Normalization in Stroke Patients [PDF]

Stroke, 2004
Background and Purpose— We sought to describe the frequency of normalization of apparent diffusion coefficient (ADC) values that are decreased in hyperacute stroke and to identify characteristics of tissue demonstrating normalization. Methods—
Jens, Fiehler, Karina, Knudsen, Thomas, Kucinski, Chelsea S, Kidwell, Jeffry R, Alger, Götz, Thomalla, Bernd, Eckert, Oliver, Wittkugel, Cornelius, Weiller, Hermann, Zeumer, Joachim, Röther   +10 more
openaire   +2 more sources

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Influence of Imaging Parameters on the Measurement of Apparent Diffusion Coefficient

Japanese Journal of Radiological Technology, 2010
The apparent diffusion coefficient (ADC) values are calculated by using signal intensity in diffusion-weighted images (DWIs) with two or more different b-value. Therefore, the signal to noise ratio (SNR) of DWI with higher b-value may have a big influence on the measured ADC value.
Ozaki, Masanori, Ogura, Akio, Muro, Isao, Miyati, Tosiaki, Tamura, Takayuki, Takahashi, Mitsuyuki, Doi, Tsukasa, Tanji, Hajime, Takahashi, Junji, Takizawa, Osamu   +9 more
openaire   +3 more sources

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

Role of diffusion MRI in characterizing benign and malignant breast lesions

Indian Journal of Radiology and Imaging, 2009
Aims: The aim of this study was to evaluate the role of MRI based diffusion-weighted imaging (DWI) and the apparent diffusion coefficient (ADC) for characterizing breast lesions in Indian patients.
Palle Lalitha, Reddy Balaji
doaj  

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Quantitative apparent diffusion coefficient mapping as a noninvasive tool for the histopathological subtyping of lung cancer: a prospective study

Alexandria Journal of Medicine
Background Lung cancer remains a leading cause of cancer-related mortality globally and in Egypt. The process of diagnosis usually includes a survey of clinical data, radiologic assessment, and histopathologic evaluation of tissue.
Ahmed M. Abdelhady, Abdel Rahman M. Khedr, Hany A. Sharaawy, Enas M. Elsayed, Ahmed M. Samir, Hadeer E. Elsebaay   +5 more
doaj   +1 more source