Results 51 to 60 of about 3,053,893 (297)

Role of Apparent Diffusion Coefficient in evaluation of rectal cancer aggressiveness [PDF]

Zagazig University Medical Journal, 2020
Objectives: To evaluate the importance of diffusion-weighted MRI imaging (DWI) as a truthful marker for detection of rectal cancer tumor aggressiveness, by studying the relation between apparent diffusion coefficient (ADC) values of the tumors, MRI ...
Mona Refaat, Mostafa Assy, ahmed salem
doaj   +1 more source

Prognostic Value of Apparent Diffusion Coefficient (ADC) in Patients with Diffuse Gliomas [PDF]

Cancers
This study aimed to evaluate potential posttreatment changes in ADC values within the tissue surrounding the enhancing lesion, particularly in areas not exhibiting MRI characteristics of involvement. Additionally, the objective was to investigate the correlations among ADC values, treatment response, and survival outcomes in individuals diagnosed with ...
Marija Bušić, Zoran Rumboldt, Dora Čerina, Željko Bušić, Krešimir Dolić   +4 more
openaire   +3 more sources

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

How to Discriminate Lung Cancer From Benign Pulmonary Nodules and Masses? Usefulness of Diffusion-Weighted Magnetic Resonance Imaging With Apparent Diffusion Coefficient and Inside/Wall Apparent Diffusion Coefficient Ratio

Clinical Medicine Insights: Oncology, 2021
Background: Although diffusion-weighted imaging (DWI) is useful for differential diagnosis between lung cancers and benign pulmonary nodules and masses (BPNMs), it is difficult to differentiate pulmonary abscesses from lung cancers because pulmonary ...
Katsuo Usuda, Shun Iwai, Aika Yamagata, Yoshihito Iijima, Nozomu Motono, Mariko Doai, Munetaka Matoba, Keiya Hirata, Hidetaka Uramoto   +8 more
doaj   +1 more source

Apparent diffusion coefficient in differentiation of pediatric posterior fossa tumors

, 2017
Purpose To investigate the contribution of preoperative apparent diffusion coefficient (ADC) values in the differential diagnosis of pediatric posterior fossa ...
Selim Doganay, Gonca Koc, Sibel Saracoglu, Kazim Z. Gumus, Soubhi Zitouni, KURTSOY, Ali, PER, Hüseyin, Huseyin Per, GUMUS, Kazim Z., Saliha Ciraci, ÜNAL, Ekrem, Olgun Kontas, SARAÇOĞLU, Sibel, Ali Kurtsoy, COŞKUN, Abdulhakim, Kontas, Olgun, Abdulhakim Coskun, Zitouni, Soubhı, Doganay, Selim, Ekrem Unal, Koc, Gonca, Ciraci, Saliha, GÜMÜŞ KAZIM, KURTSOY ALİ, COŞKUN ABDULHAKİM, ÜNAL EKREM, KONTAŞ OLGUN, ÇIRACI SALİHA, PER HÜSEYİN, SARAÇOĞLU SİBEL, DOĞANAY SELİM, KOÇ GONCA, ZITOUNI SOUBHI i   +32 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Apparent Diffusion Coefficient in Predicting the Preoperative Grade of Meningiomas

Journal of the College of Physicians and Surgeons Pakistan, 2020
To investigate the relationship between the apparent diffusion coefficients (ADC) value obtained from magnetic resonance imaging (MRI) and histopathologic grade of meningiomas.Observational study.Department of Radiology, Istanbul Medeniyet University, School of Medicine, Istanbul, Turkey between January 2015 and June 2019.Data of 45 patients with ...
Basak, Atalay, Suna Sahin, Ediz, Nurver Ozel, Ozbay   +2 more
openaire   +3 more sources

On the timing characteristics of the apparent diffusion coefficient contrast in fMRI [PDF]

Magnetic Resonance in Medicine, 2002
AbstractFor the past 10 years, functional MRI (fMRI) has seen rapid progress in both clinical and basic science research. Most of the imaging techniques are based on the blood oxygenation level‐dependent (BOLD) contrast which arises from the field perturbation of the paramagnetic deoxyhemoglobin due to the mismatch between the local oxygen demand and ...
Stacey L, Gangstead, Allen W, Song
openaire   +2 more sources

Diagnostic efficacy of apparent diffusion coefficient measurements in differentiation of malignant intra-axial brain tumors

, 2021
Background/aim: To evaluate diagnostic efficacy of the apparent diffusion coefficient measurements from tumor (ADC(t)) and tumor circumference hyperintensities (ADC(tch)) in different types of malignant intra-axial brain ...
Eyüboğlu, İlker, Cakir, Ismet Mirac, Aslan, Serdar, Sarı, Ahmet, SARI, AHMET   +4 more
core   +1 more source