Results 91 to 100 of about 3,053,893 (297)

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

Detection and modeling of non-Gaussian apparent diffusion coefficient profiles in human brain data [PDF]

, 2002
This work details the observation of non-Gaussian apparent diffusion coefficient (ADC) profiles in multi-direction, diffusion-weighted MR data acquired with easily achievable imaging parameters (b 1000 s/mm2).
BARKER, G. J.; id_orcid, Arridge, S.R., ALEXANDER, D. C., Alexander, D.C., ARRIDGE, S. R., Barker , G.J.   +5 more
core   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

Multi-centre reproducibility of diffusion MRI parameters for clinical sequences in the brain. [PDF]

, 2015
The purpose of this work was to assess the reproducibility of diffusion imaging, and in particular the apparent diffusion coefficient (ADC), intra-voxel incoherent motion (IVIM) parameters and diffusion tensor imaging (DTI) parameters, across multiple ...
Raschke, F, Leach, MO, Rossiter, J, Clayden, JD, Miyazaki, K, Morgan, PS, Rodriguez, D, Wilson, M, Saunders, DE, Auer, DP, Peet, Andrew, Barrick, TR, Peet, AC, Davies, NP, Grundy, R, Clark, CA, Clark, Christopher, Hales, PW, Wilson, Martin; id_orcid, Gwilliam, MN, Grech-Sollars, M, Howe, FA, Grech-Sollars, Matthew, Gill, SK, Banks, T   +24 more
core   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Apparent Diffusion Coefficients of Breast Tumors: Clinical Application

Magnetic Resonance in Medical Sciences, 2008
To evaluate the usefulness of apparent diffusion coefficient (ADC) for the differential diagnosis of breast tumors and to determine the relation between ADC and tumor cellularity.One hundred and thirty-six female patients (age range, 17-83 years; average age, 51.7 years) with 140 histologically proven breast tumors underwent diffusion-weighted magnetic
HATAKENAKA, Masamitsu, SOEDA, Hiroyasu, YABUUCHI, Hidetake, MATSUO, Yoshio, KAMITANI, Takeshi, ODA, Yoshinao, TSUNEYOSHI, Masazumi, HONDA, Hiroshi   +7 more
openaire   +3 more sources

Notch inhibitor can attenuate apparent diffusion coefficient and improve neurological function through downregulating NOX2-ROS in severe traumatic brain injury

, 2018
Hong-Mei Zhang,1,2 Wei Chen,3 Rui-Ning Liu,1 Yan Zhao1 1Emergency Center, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei, People’s Republic of China; 2Emergency Department, The Second Medical College of Jinan University, Shenzhen ...
Chen W, Liu RN, Zhang HM, Zhao Y
core  

ICACE-Chloride-Diffusion-Coefficient-Paper.pdf

, 2019
Predicting service life is an essential aspect of long-term sustainability of any reinforced concrete (RC) infrastructure in a marine environment. The service life of RC is primarily affected by chloride induced corrosion of embedded reinforcement and ...
Naqib Mashrur (6419105)
core   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

Correlation of minimum apparent diffusion coefficient with maximum standardized uptake on fluorodeoxyglucose PET-CT in patients with rectal adenocarcinoma [PDF]

, 2014
PURPOSE:The aim of this study was to retrospectively assess the correlation between minimum apparent diffusion coefficient (ADCmin) values obtained from diffusion-weighted magnetic resonance imaging (MRI) and maximum standardized uptake values (SUVmax ...
Ayşe Erden, Hale Çolakoğlu Er, Ethem Geçim, N. Özlem Küçük   +3 more
core   +1 more source