Results 111 to 120 of about 16,848 (291)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Influence of feed form and corn particle size on nutrient digestibility and energy utilization by young turkeys

Revista Brasileira de Zootecnia, 2012
A digestibility trial with 16 to 21-day-old turkeys was conducted to study the effects of feed form and corn particle size on the coefficient of total intestinal tract apparent digestibility of dry matter (DM), nitrogen (N), ether extract (EE), aparent ...
André Favero, Alex Maiorka, Ana Vitória Fischer da Silva, Fabio Luiz de Paula Valle, Samuel Augusto dos Santos, Keysuke Muramatsu   +5 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Utilization of Garlic with and Without Addition of Enzymes on Black-capped Lory (Lorius Lory Linnaeus, 1758) in Captive Breeding [PDF]

, 2017
Phytogenic feed additives are plant-derived product such as herbs, spices, and essential oils used in animal feed to improve their performances and health. Garlic (Allium sativum) is well-known as a spice and herbal medicine.
Maharani, S. (Sinta), Nugroho, H. A. (Herjuno), Sari, A. P. (Andri)   +2 more
core  

The true and apparent metabolizable energy values of fats in adults roosters.

Japanese poultry science, 1986
黄色グリースおよび大豆油の見かけの代謝エネルギー(AMEn)および真の代謝エネルギー(TMEおよびTMEn)を白色レグホーン種雄成鶏(6ヶ月齢)を用い,基礎飼料としてトウモロコシ,大豆粕および配合飼料(大雛用)を用い油脂水準(5,10および15%)を変えて測存した。黄色グリース,大豆油のAMEn値は基礎飼料に大豆粕飼料を用いた場合,トウモロコシ,配合飼料に比べ有意に高い値が得られた。また油脂水準が高まると,いずれの値も低下の傾向を示した。黄色グリース,大豆油のTMEおよびTMEn値はAMEnと同様,大豆粕飼料を用いた場合,トウモロコシ,配合飼料に比べ高い値が得られたが,大豆油は黄色グリースほどの違いは認められなかった。油脂水準が高まるとTME値は高まる傾向を示したがTMEn値は低下の傾向を示した ...
openaire   +2 more sources

Apparent metabolizable and net energy values of corn and soybean meal for broiler breeding cocks

Poultry Science, 2017
The AME and net energy (NE) values of 4 corn varieties, including 2 normal corn varieties (Zheng Dan 958 and Xian Yu 335), and one each of waxy corn and sweet corn, and 2 soybean meal samples including regular (RSBM) and dehulled soybean meal (DSBM), were determined in 2 experiments for broiler breeding cocks using the indirect calorimetry method.
W, Liu, G H, Liu, R B, Liao, Y L, Chang, X Y, Huang, Y B, Wu, H M, Yang, H J, Yan, H Y, Cai   +8 more
openaire   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Starch digestibility and apparent metabolizable energy of western Canadian wheat market classes in broiler chickens

Poultry Science, 2018
Wheat is the primary grain fed to poultry in western Canada, but its nutritional quality, including the nature of its starch digestibility, may be affected by wheat market class. The objectives of this study were to determine the rate and extent of starch digestibility of wheat market classes in broiler chickens, and to determine the relationship ...
N D, Karunaratne, D A, Abbott, P J, Hucl, R N, Chibbar, C J, Pozniak, H L, Classen   +5 more
openaire   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Composição química, valores energéticos e aminoácidos digestíveis verdadeiros de farinhas de vísceras para aves Chemical composition, energetic values and real digestible amino acid of different viscera meals for poultry

Revista Brasileira de Zootecnia, 2010
Objetivou-se determinar a composição energética e aminoacídica, os coeficientes de metabolizabilidade da energia e a digestibilidade de farinhas de vísceras para aves. Utilizou-se o método da alimentação forçada com galos adultos cecectomizados.
Cinthia Eyng, Ricardo Vianna Nunes, Horacio Santiago Rostagno, Luiz Fernando Teixeira Albino, Christiane Garcia Vilela Nunes, Luís Daniel Giusti Bruno   +5 more
doaj   +1 more source