Results 71 to 80 of about 6,385,914 (227)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

PENGARUH BERBAGAI ENKAPSULAN DALAM PROSES ENKAPSULASI ASAM SITRAT SEBAGAIACIDIFIER DALAM PAKAN AYAM PEDAGING TERHADAP KECERNAAN PROTEIN DAN ENERGI MET ABOLIS

Jurnal Ilmu-Ilmu Peternakan, 2009
The aim of this research was to examine the influence of several encapsulants in encapsulating citric acid used as acidifier on protein digestibility and metabolizable energy in broilers.
M. Halim Natsir
doaj  

Adjustment of equations to predict the metabolizable energy of corn for meat type quails

Semina: Ciências Agrárias, 2015
The metabolizable energy (ME) determination for foods used in quail diets, through metabolism assays, takes time, infrastructure and financial resources, which makes the development of prediction equations based on proximal composition of foods to ...
Tiago Junior Pasquetti , Paulo Cesar Pozza, Antonio Claudio Furlan, Leandro Dalcin Castilha , Laura Marcela Diaz-Huepa , Marcelise Regina Fachinello , Simara Márcia Marcato , Wesley Tanamati   +7 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Effect of corn oil on the digestibility and economic viability of broiler chicken feed, and on the bromatological composition of breast meat

Semina: Ciências Agrárias, 2016
The objective of this study was to evaluate the digestibility, economic efficiency, and composition of breast muscle in broiler chickens fed with a diet containing corn oil as an alternative replacement to soybean oil.
Marcella Machado Antunes, João Paulo Rodrigues Bueno, Evandro de Abreu Fernandes, Carolina Magalhães Caires Carvalho, Fernanda Heloisa Litz, Julyana Machado da Silva Martins, Marina Cruvinel Assunção Silva, André Lucas Silva Masculi, Mara Regina Bueno de Mattos Nascimento   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A note on the apparent digestibility of energy and protein in dried poultry excreta

, 1970
SUMMARYThe nutritional value of dried poultry excreta was investigated by determining the apparent digestibility of dry matter, organic matter, nitrogen, energy and copper in five diets containing 0 to 100% of this feed. Dried poultry excreta supplied 20·
D. W. Knight, B. G. Lowman
core   +1 more source

Kecernaan protein dan energi metabolis akibat pemberian zat aditif cair buah naga merah (Hylocereus polyrhizus) pada burung puyuh japonica betina umur 16-50 hari

Jurnal Ilmu-Ilmu Peternakan, 2015
Digestibility of crude protein and energy is used to measure digestibility in poultry, digestible shows of feed substances absorbed by the body which will affect the productivity of quail.
Meina Yuniarti, Fajar Wahyono, Vitus Dwi Yunianto B. I   +2 more
doaj   +1 more source