Results 71 to 80 of about 9,888,987 (278)
Characterization of optical fiber imaging bundles for swept-source optical coherence tomography [PDF]
Fiber imaging bundles have been investigated for use in endoscopic optical coherence tomography (OCT) systems, to obviate the requirement for scanning components within the endoscope probe section.
Helen D. Ford +3 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
We present here an assessment of in situ hyperspectral bio-optical variability in the Vaigat-Disko Bay and Godthabsfjord along the southwest coast of Greenland.
Veloisa J. Mascarenhas +2 more
doaj +1 more source
Multiple Wavelength Free-Space Laser Communications [PDF]
Free-space optical communications systems in the atmosphere, based on intensity modulation and direct detection, are heavily affected by fading caused by turbulence cells of varying scale and motion.
Perlot, Nicolas +9 more
core +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Optical indicators of DOM photoreactivity: principles, applications, and possible improvements
Sunlit waters transform dissolved organic matter (DOM) from a passive carbon pool into a source of reactive chemistry. Optical indicators derived from ultraviolet-visible absorption and fluorescence spectroscopy are commonly used to characterize this ...
Ye Zhang +4 more
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Optical tweezers enable noninvasive manipulation of microscopic objects through piconewton‐scale optical forces generated by a tightly focused laser beam. Trapping efficiency is known to depend strongly on particle size and refractive index, although the
Ana Dávila +3 more
doaj +1 more source

