Results 31 to 40 of about 124,745 (257)

Synthesis, characterization, and pharmacological evaluation of some metal complexes of quercetin as P-gp inhibitors

Future Journal of Pharmaceutical Sciences, 2021
Background Six different metal complexes of quercetin (Cu, Zn, Co, Vd, Mo, Ni) were synthesized, purified, and characterized by their physical and spectral (UV, IR) data.
Kirankumar Shastrala, Sirisha Kalam, Kumaraswamy Damerakonda, Sharvana Bhava Bandaru Sheshagiri, Hitesh Kumar, Ramu Guda, Mamatha Kasula, Satish Kumar Bedada   +7 more
doaj   +1 more source

Permeability model for shale and ultra-tight gas formations: Critical insights into the impact of dynamic adsorption

Energy Reports, 2021
Gas transport in ultra-tight rock is non-Darcian. In addition to continuum flow, there are multiple other flow mechanisms such as slip flow and pore and surface diffusion. Various multi-physics models have been put forth in the literature to forecast the
Clement Afagwu, Saad Alafnan, Mohamed A. Mahmoud, Shirish Patil   +3 more
doaj   +1 more source

Erythrocyte Fatty Acid Composition and Apparent Permeability to Non-Electrolytes.

Experimental Biology and Medicine, 1964
SummaryVariations in the nature of the dietary fat resulted in changes in the mixed fatty acid composition of rat erythrocytes. An increase in linoleate content of the diet led to an increased cellular linoleate and arachidonate content whereas diets deficient in linoleate resulted in accumulation of palmitoleic, oleic and eicosatrienoic acids.
B L, WALKER, F A, KUMMEROW
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Apparent Permeability Model for Shale Gas Reservoirs Considering Multiple Transport Mechanisms

Geofluids, 2018
Shale formation is featured in nanopores and much gas adsorptions. Gas flow in the shale matrix is not a singular viscous flow, but a combination of multiple mechanisms. Much work has been carried out to analyze apparent permeability of shale, but little
Shijun Huang, Yonghui Wu, Linsong Cheng, Hongjun Liu, Yongchao Xue, Guanyang Ding   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Applicability Analysis of Klinkenberg Slip Theory in the Measurement of Tight Core Permeability

Energies, 2019
The Klinkenberg slippage theory has widely been used to obtain gas permeability in low-permeability porous media. However, recent research shows that there is a deviation from the Klinkenberg slippage theory for tight reservoir cores under low-pressure ...
Jirui Zou, Xiangan Yue, Weiqing An, Jun Gu, Liqi Wang   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source