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Gut peptides and the regulation of appetite

Obesity Reviews, 2006
SummaryThere is a growing worldwide epidemic of obesity. Obese people have a higher incidence of type 2 diabetes and cardiovascular disease, and hence present increasing social, financial and health burdens. Weight loss is always difficult to achieve through lifestyle changes alone, and currently licensed anti‐obesity drug treatments, such as orlistat ...
M S B, Huda   +2 more
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Robust modeling of appetite regulation

Journal of Theoretical Biology, 2011
The interaction between appetite activation and the energy content of the brain and the body is mathematically modeled. General influence functions with saturation are used to describe the interaction. The resulting class of models is investigated with respect to the circadian periodicity of human food intake. We show that very weak and physiologically
Göbel, B.   +4 more
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Appetite Regulation: An Overview

Thyroid, 2007
Obesity is a major public health problem associated with morbidity and mortality and continues to increase worldwide. This review focuses on the regions of the brain that are important in appetite regulation and the circulating factors implicated in the control of food intake.
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Appetite Regulation by Gut Peptides

Annual Review of Nutrition, 1990
A number of gastrointestinal hormones that are released from the gut in response to intraluminal food stuffs have been shown to play a role in producing satiety. Some of these hormones apparently activate ascending vagal fibers that send messages to the nucleus tractus solitarius, and perhaps from there messages are sent to the paraventricular nucleus ...
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Hypothalamic neuropeptides and the regulation of appetite

Neuropharmacology, 2012
Neuropeptides released by hypothalamic neurons play a major role in the regulation of feeding, acting both within the hypothalamus, and at other appetite regulating centres throughout the brain. Where classical neurotransmitters signal only within synapses, neuropeptides diffuse over greater distances affecting both nearby and distant neurons ...
Jennifer A, Parker, Stephen R, Bloom
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Appetite regulation and energy balance

Acta Paediatrica, 2005
AbstractThe decision to begin eating or to stop eating is a complex process. Hunger is primarily driven by hunger signals, like ghrelin and neuropeptide Y, originating from the gastrointestinal tract and from the hypothalamus. The hunger signals stimulate the seeking of food and the eating, being activating for the body and mind.
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Regulation of appetite in frail persons

Clinics in Geriatric Medicine, 2002
Aging is often accompanied by anorexia of aging, described as a decline in appetite resulting in a lower dietary intake, followed by unexplained weight loss and adverse effects on health. This article discusses the main causes of a lack of appetite in frail elderly people.
van Staveren, W.A.   +2 more
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Neuropeptide Regulation of Appetite and Weight*

Endocrine Reviews, 1987
IN THE last decade, the explosive increase in our knowledge of neuropeptides has demonstrated that the release of peptides from the gastrointestinal tract can modulate behavior; and, contrariwise, gastrointestinal peptides have been shown to be synthesized and released in the central nervous system and act as neurotransmitters.
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Appetite regulation

Postgraduate Medicine, 1985
PreviewAlthough most scientific research on the mechanisms involved in appetite regulation has been done in animals, cautious application to humans of at least some study results may be valid. Drs Morley and Levine, respected authorities in the field of endocrinology, walk the reader through the sometimes-complex findings and discuss some practical ...
J E, Morley, A S, Levine
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Gut hormones and appetite regulation

Current Opinion in Endocrinology, Diabetes & Obesity
Purpose of review Various gut hormones interact with the brain through delicate communication, thereby influencing appetite and subsequent changes in body weight. This review summarizes the effects of gut hormones on appetite, with a focus on recent research. Recent findings Ghrelin
So-Hyeon, Hong, Kyung Mook, Choi
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