Results 1 to 10 of about 43,755 (242)

Targeting Cancer Cachexia: A Mechanistic Evaluation of Anti-GDF-15 Antibody-Based Combination Therapies. [PDF]

J Cachexia Sarcopenia Muscle
ABSTRACT Background In a recent Phase 2 trial in patients with cancer cachexia, the anti‐GDF‐15 antibody ponsegromab resulted in increased body weight, appetite, muscle mass and physical activity. This study provides compelling evidence that targeting the GDF‐15 pathway may offer a viable therapeutic strategy, while raising new mechanistic questions ...
Breen DM, Joaquim S, Paulhus BL, Bennett D, Bernardo B, Collins S, Esquejo RM, Kim-Muller JY, Lin L, Peloquin M, Wu Z, Qiao S, Stansfield JC, Zhang BB, Rossulek MI.   +14 more
europepmc   +2 more sources

Ghrelin's role in sleep and sleep deprivation: a narrative review. [PDF]

Front Psychiatry
Ditmer M, Wojtera A, Gabryelska A, Turkiewicz S, Białasiewicz P, Strzelecki D, Sochal M.   +6 more
europepmc   +1 more source

The role of LEAP2 on cognitive impulsivity after refeeding: evidence from a preclinical study in female mice and from patients with anorexia nervosa. [PDF]

Transl Psychiatry
Tezenas du Montcel C, Hamelin H, Lebrun N, Duriez P, Ramoz N, Gorwood P, Viltart O, Tolle V.   +7 more
europepmc   +1 more source

Ghrelin protects against cell death in myocardial ischaemia: Emerging role of microRNA. [PDF]

Exp Physiol
Katare R, Erickson JR, Schwenke DO.
europepmc   +1 more source

Comparative Analysis of Adipokines and Growth Factors in Preterm and Term Breast Milk and Their Role in Infant Growth. [PDF]

Curr Nutr Rep
Guler TT, Fisunoglu M.
europepmc   +1 more source

The role of nitric oxide signaling in reward induced by ghrelin and alcohol in mice

, 2016
Joel Kjellgren
openalex   +1 more source

Plasma Ghrelin Concentrations Were Altered with Oestrous Cycle Stage and Increasing Age in Reproductively Competent Wistar Females

, 2016
Michelle L. Johnson, M. Jill Saffrey, Victoria Taylor   +2 more
openalex   +2 more sources

KARIs, Ghrelin Receptor Agonists With Excellent Brain Permeability, Increase Food Intake and Attenuate the Muscle Loss in Mice. [PDF]

J Cachexia Sarcopenia Muscle
Yoon HJ, Han WH, Kim SB, Lee WG, Choi SY, Choi BJ, Pang M, Choi MK, Lee J, Song IS, Park MH, Jin HK, Bae JS.   +12 more
europepmc   +1 more source

Ghrelin modulates testicular damage in a cryptorchid mouse model

, 2017
Enrica Bianchi, Kim Boekelheide, Mark Sigman, Susan J. Hall, Kathleen Hwang   +4 more
openalex   +2 more sources