Results 31 to 40 of about 43,755 (242)
Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity
Periodontology 2000, EarlyView., 2023 Abstract Noncommunicable diseases (NCDs) are multifactorial, long‐term, chronic conditions that represent a burden to health‐care systems worldwide as they can only be controlled rather than cured; hence, they require long‐term care. With the exponential increase in NCDs, the occurrence of individuals presenting with more than one chronic disease is ...
Crystal Marruganti +2 more
wiley +1 more source
, 2017 Ghrelin is a pleiotropic hormone, whose effect on growth hormone secretion, through the growth hormone secretagogue (GHS) receptor, is one of its many actions. Relationships between GHS receptor gene variants and human height, both in healthy individuals and in patients with growth disorders have been identified.
Perchard, Reena; id_orcid 0000-0002-3072-0055 +1 more
openaire +3 more sources
Ghrelin and ghrelin receptor modulation of psychostimulant action [PDF]
Frontiers in Neuroscience, 2013 Ghrelin (GHR) is an orexigenic gut peptide that modulates multiple homeostatic functions including gastric emptying, anxiety, stress, memory, feeding, and reinforcement. GHR is known to bind and activate growth-hormone secretagogue receptors (termed GHR-Rs).
Wellman, Paul J. +2 more
openaire +3 more sources
Different forms of ghrelin exhibit distinct biological roles in tilapia
Frontiers in Endocrinology, 2013 Ghrelin has been identified in all vertebrate classes, including sharks. Each species possesses multiple forms of ghrelin that vary in peptide length and acyl modifications (e.g.
Larry eRiley
doaj +1 more source
Altered lipid and salt taste responsivity in ghrelin and GOAT null mice. [PDF]
PLoS ONE, 2013 Taste perception plays an important role in regulating food preference, eating behavior and energy homeostasis. Taste perception is modulated by a variety of factors, including gastric hormones such as ghrelin. Ghrelin can regulate growth hormone release,
Huan Cai +7 more
doaj +1 more source
, 2014 The 28-amino acid peptide ghrelin was originally identified as an orexigenic hormone involved in the regulation of an organism’s energy homeostasis. Besides its role in metabolic processes, accumulating evidence suggests that ghrelin also plays an important role in the cognitive aspects of energy homeostasis, in particular learning and memory.
Kunath, N., Dresler, M.
openaire +1 more source
Cell Metabolism, 2014 The initial discovery of ghrelin as a potent orexigenic hormone raised excitement about a new direction for possibly treating eating disorders. McFarlane et al. (2014) show that with deletion of ghrelin-producing cells from an adult animal, there is little effect on appetitive behaviors but significant implications for glucose homeostasis.
Sleeman, Mark W., Spanswick, David C.
openaire +2 more sources
Journal of Obesity & Metabolic Syndrome, 2017 Background : Desacyl ghrelin is acylated by ghrelin O-acyltransferase (GOAT) and converted to acyl ghrelin. To date, little is known about the relationship among the levels of these two forms of ghrelin, GOAT level, and insulin resistance in Asian ...
Young Hye Cho +11 more
doaj +1 more source
Altered ghrelin secretion in mice in response to diet-induced obesity and Roux-en-Y gastric bypass
Molecular Metabolism, 2014 The current study examined potential mechanisms for altered circulating ghrelin levels observed in diet-induced obesity (DIO) and following weight loss resulting from Roux-en-Y gastric bypass (RYGB).
Aki Uchida +5 more
doaj +1 more source
Ablation of ghrelin O-acyltransferase does not improve glucose intolerance or body adiposity in mice on a leptin-deficient ob/ob background. [PDF]
PLoS ONE, 2013 Type 2 Diabetes is a global health burden and based on current estimates will become an even larger problem in the future. Developing new strategies to prevent and treat diabetes is a scientific challenge of high priority. The stomach hormone ghrelin has
Henriette Kirchner +5 more
doaj +1 more source