Results 21 to 30 of about 43,755 (242)
Aquaculture Reports, 2023 Ghrelin has been well known as an orexigenic hormone that regulates appetite and energy metabolism in animals. Recent studies imply the regulatory function of ghrelin on ovary development, however, the mechanism about the effects of ghrelin on key ...
Jiamin Pi +7 more
doaj +1 more source
A review on ghrelin and fish reproduction
Reproduction and Breeding, 2021 Ghrelin is a multifunctional peptide hormone which dominantly secreted in stomach and intestine. Ghrelin involves in growth control, food intake, energy balance, and reproductive process.
Huan Zhong, Yi Hu, Fan Yu
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Unacylated ghrelin counteracts mitochondrial dysfunction and neuromuscular junction disruption in cancer cachexia. [PDF]
Am J Physiol Cell PhysiolAhn B +4 more
europepmc +2 more sources
Changes in subcellular distribution of n-octanoyl or n-decanoyl ghrelin in ghrelin-producing cells
Frontiers in Endocrinology, 2013 Background: The enzyme ghrelin O-acyltransferase (GOAT) catalyzes the acylation of ghrelin. The molecular form of GOAT, together with its reaction in vitro, has been reported previously.
Yoshihiro eNishi +8 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 The role of high-fat diet (HFD) induced gut microbiota alteration and Ghrelin as well as their correlation in benign prostatic hyperplasia (BPH) were explored in our study. The gut microbiota was analyzed by 16s rRNA sequencing.
Meng Gu +7 more
doaj +1 more source
“A LEAP 2 conclusions? Targeting the ghrelin system to treat obesity and diabetes”
Molecular Metabolism, 2021 Background: The hormone ghrelin stimulates food intake, promotes adiposity, increases body weight, and elevates blood glucose. Consequently, alterations in plasma ghrelin levels and the functioning of other components of the broader ghrelin system have ...
Deepali Gupta +4 more
doaj +1 more source
Journal of Cachexia, Sarcopenia and Muscle, 2010 Ghrelin, a natural ligand for the growth hormone (GH)‐secretagogue receptor, is primarily produced in the stomach. Administration of ghrelin stimulates food intake and GH secretion in both animals and humans. Ghrelin is the only circulating hormone known to stimulate appetite in humans.
Akamizu, Takashi, Kangawa, Kenji
openaire +2 more sources
Insights from engraftable immunodeficient mouse models of hyperinsulinaemia
Scientific Reports, 2017 Hyperinsulinaemia, obesity and dyslipidaemia are independent and collective risk factors for many cancers. Here, the long-term effects of a 23% Western high-fat diet (HFD) in two immunodeficient mouse strains (NOD/SCID and Rag1 −/−) suitable for ...
Michelle L. Maugham +11 more
doaj +1 more source
The oncogenic role of the In1-ghrelin splicing variant in prostate cancer aggressiveness
Molecular Cancer, 2017 Background The Ghrelin-system is a complex, pleiotropic family composed of several peptides, including native-ghrelin and its In1-ghrelin splicing variant, and receptors (GHSR 1a/b), which are dysregulated in various endocrine-related tumors, where they ...
Daniel Hormaechea-Agulla +18 more
doaj +1 more source
Hindbrain ghrelin receptor signaling is sufficient to maintain fasting glucose. [PDF]
PLoS ONE, 2012 The neuronal coordination of metabolic homeostasis requires the integration of hormonal signals with multiple interrelated central neuronal circuits to produce appropriate levels of food intake, energy expenditure and fuel availability.
Michael M Scott +8 more
doaj +1 more source