Results 21 to 30 of about 31,273 (172)

Ghrelin cell–expressed insulin receptors mediate meal- and obesity-induced declines in plasma ghrelin

open access: yesJCI Insight, 2021
Mechanisms underlying postprandial and obesity-associated plasma ghrelin reductions are incompletely understood. Here, using ghrelin cell–selective insulin receptor–KO (GhIRKO) mice, we tested the impact of insulin, acting via ghrelin cell–expressed ...
Kripa Shankar   +9 more
doaj   +1 more source

Ablation of ghrelin O-acyltransferase does not improve glucose intolerance or body adiposity in mice on a leptin-deficient ob/ob background. [PDF]

open access: yesPLoS ONE, 2013
Type 2 Diabetes is a global health burden and based on current estimates will become an even larger problem in the future. Developing new strategies to prevent and treat diabetes is a scientific challenge of high priority. The stomach hormone ghrelin has
Henriette Kirchner   +5 more
doaj   +1 more source

GABAB Receptor Blockade Prevents Antiepileptic Action of Ghrelin in the Rat Hippocampus [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2013
Purpose: Ghrelin has been shown to have antiepileptic function. However, the underlying mechanisms by which, ghrelin exerts its antiepileptic effects are still unclear.
Zohreh Ataie   +5 more
doaj   +1 more source

From an Empty Stomach to Anxiolysis: Molecular and Behavioral Assessment of Sex Differences in the Ghrelin Axis of Rats

open access: yesFrontiers in Endocrinology, 2022
Ghrelin, a stomach-produced hormone, is well-recognized for its role in promoting feeding, controlling energy homeostasis, and glucoregulation. Ghrelin’s function to ensure survival extends beyond that: its release parallels that of corticosterone, and ...
Stina Börchers   +16 more
doaj   +1 more source

Ghrelin: Ghrelin as a Regulatory Peptide in Growth Hormone Secretion [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Background: Ghrelin is a type of growth hormone (GH) secretagogue that stimulates the release of GH. It is a first hormone linking gastrointestinal-pituitary axis.
Nazli Khatib   +6 more
doaj   +1 more source

Acylation, a Conductor of Ghrelin Function in Brain Health and Disease

open access: yesFrontiers in Physiology, 2022
Acyl-ghrelin (AG) is an orexigenic hormone that has a unique octanoyl modification on its third serine residue. It is often referred to as the “hunger hormone” due to its involvement in stimulating food intake and regulating energy homeostasis.
Alanna S. Thomas   +4 more
doaj   +1 more source

Increased ghrelin but low ghrelin-reactive immunoglobulins in a rat model of methotrexate chemotherapy-induced anorexia

open access: yesFrontiers in Nutrition, 2016
Background and aims: Cancer chemotherapy is commonly accompanied by mucositis, anorexia, weight loss and anxiety independently from cancer-induced anorexia-cachexia, further aggravating clinical outcome.
Marie François   +12 more
doaj   +1 more source

Structure and Physiological Actions of Ghrelin

open access: yesScientifica, 2013
Ghrelin is a gastric peptide hormone, discovered as being the endogenous ligand of growth hormone secretagogue receptor. Ghrelin is a 28 amino acid peptide presenting a unique n-octanoylation modification on its serine in position 3, catalyzed by ghrelin
Christine Delporte
doaj   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

open access: yesAdvanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu   +2 more
wiley   +1 more source

Very Long‐Term Outcomes of Laparoscopic Adjustable Gastric Banding in a Japanese Cohort: A Single‐Center 15‐Year Follow‐Up Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Long‐term outcomes of laparoscopic adjustable gastric banding (LAGB) in Japan were retrospectively evaluated in 28 patients with up to 15 years of follow‐up. LAGB achieved sustained long‐term weight reduction in selected patients; however, recurrence of metabolic comorbidities increased during extended follow‐up.
Yuichi Endo   +12 more
wiley   +1 more source

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