Results 91 to 100 of about 403,445 (285)

The New Methodology for Analyzing the Regulatory Impact of a Legal Act: Pros and Cons [PDF]

open access: yesProblemi Ekonomiki, 2016
Advantages and problems of the existing methodologies for analyzing the impact and monitoring of the effectiveness of a regulatory act (RIA) have been evaluated.
Chechetovа-Terashvili Tetiana M.   +2 more
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Integral Indicator for Assessing the Development of Renewable Energy Sources [PDF]

open access: yesProblemi Ekonomiki, 2018
To assess the development of renewable energy sources, the structuring of indicators in three groups is performed, namely: economic, environmental, and social ones.
Khazan Pavlo V.
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Public formations in municipalities as a form of public control over the local power [PDF]

open access: yesТеория и практика общественного развития, 2014
The article deals with the main problems of public control over local authorities’ activities by means of Public Chambers and Public Councils. The au-thor comes to the conclusion that it's necessary to develop the clear principles of formation of these ...
Anosova Vera Vasilievna
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The Employment Interview as a Recruitment Device [PDF]

open access: yes, 1988
[Excerpt] More directly to the point of this paper, differences in the relative importance of recruitment versus selection are hypothesized to influence the conduct, and outcomes, of the employment interview. This can occur in several ways.
Rynes, Sara L.
core   +1 more source

Foodomics Applications

open access: yes, 2018
Foodomics is the discipline that studies the food and nutrition domains through the application and integration of advanced omics technologies. This chapter summarizes the different strategies used in Foodomics for data analysis as well as the existing limitations and challenges that still need to be overcome in this new discipline.
León, Carlos   +2 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Influence of response instructions and response format on applicant perceptions of a situational judgement test for medical school selection

open access: yesBMC Medical Education, 2018
Background This study examined the influence of two Situational Judgement Test (SJT) design features (response instructions and response format) on applicant perceptions.
Wendy E. De Leng   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy