Results 111 to 120 of about 403,445 (285)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Comparison of borderline personality traits, interpersonal forgiveness and listening styles in applicant woman and non-applicant divorce [PDF]
مجله علوم روانشناختیBackground: One of the most important challenges that all societies face is the reality of divorce, which is constantly increasing. On the other hand, based on previous studies, borderline personality traits, interpersonal forgiveness, and listening ...
Rana Khosravi, Mozhgan Sepahmansour
doaj
Are homosexuals discriminated against in the hiring process? [PDF]
This paper presents the first field experiment on sexual orientation discrimination in the hiring process in the Swedish labor market. Job applications were sent to about 4,000 employers in 10 different occupations in Sweden.
Ahmed, Ali +2 more
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Security for costs and the foreign resident claimant [PDF]
, 2009 Discusses the courts' discretion under CPR r.25.13(2)(a) to order security for costs against a claimant resident outside the Brussels regime. Analyses the wording of the rule, noting the difference between "resident" and "ordinarily resident" and the ...
Ching, J
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Cross-lender variation in home mortgage lending [PDF]
A lender-specific analysis of differences in minority and low-income mortgage loan originations using new applicant-level data gathered under the Home Mortgage Disclosure Act of 1975.Home Mortgage Disclosure Act ; Mortgages ; Discrimination in mortgage ...
Mark S. Sniderman +2 more
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Health ExpectationsIntroduction In the United Kingdom, community pharmacists (CPs) are increasingly being used to provide supplemental care for patients with specific conditions while the NHS is under pressure from declining GP numbers alongside a rising demand for ...
Evelyn Brunsdon +9 more
doaj +1 more source
European Union Financial Transfers to Applicant Countries [PDF]
The overall financial framework of the EU for the years 2000.2006 provides for specific transfers in favour of the applicant countries during future eastern enlargement.
Magdalena Tomczynska
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