Results 121 to 130 of about 403,445 (285)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Allocating Awards Across Noncomparable Categories [PDF]

open access: yes
Suppose an agency awards a …xed number of prizes to applicants in different categories such that the applicant-to-winner ratio is constant by category.
Lonnie Magee, Michael R. Veall
core  

Managerial valuation of applicant credentials and personal traits in hiring decisions [PDF]

open access: yes, 2011
We study how managers value applicant credentials and personal traits in hiring decisions. Using the ordered probit model, we confirm previous results - managers rank applicant traits higher than credentials.
Co, Catherine Y.   +3 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Involvement of Social Media Profiles in the Hiring Process [PDF]

open access: yes, 2018
In recent years, social media has become a popular tool in the recruitment and selection process for employers. Many companies see it as a more cost efficient screening process than traditional background checks and interviews.
Lant, Theresa, Mejias, Ashley
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Managerial Valuation of Applicant Credentials and Personal Traits in Hiring Decisions [PDF]

open access: yes
We study how managers value applicant credentials and personal traits in hiring decisions. Using the ordered probit model, we confirm previous results – managers rank applicant traits higher than credentials.
Co, Catherine Y.   +3 more
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

What do you mean by "mobile"? Multi-applicant inventors in the European Bio-Technology Industry [PDF]

open access: yes
Many recent papers dealing with the issue of knowledge spillovers have relied on patent data to extract information on so-called mobile inventors that is inventors designated by patent applications filed by different companies. In this paper we follow in
Francesco Laforgia, Francesco Lissoni
core  

European Court of Human Rights : Olaffson v. Iceland [PDF]

open access: yes, 2017
According to the European Court of Human Rights (ECtHR), Iceland has breached the right to freedom of expression of the editor of a web-based media site, by holding him liable for defamation. The applicant in this case is Mr.
Voorhoof, Dirk
core   +1 more source

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