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Mountain West Digital Library Metadata Application Profile Version 3 2019

open access: yes, 2019
Mountain West Digital Library (MWDL) published this revised metadata application profile in December 2019. Version 3 supersedes Version 2 (2011)
Mountain West Digital Library Metadata Application Profile Task Force (2019)
core  

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Crop nutrient application rates [PDF]

open access: yes, 2014
This guide provides information on how to match nutrient rate to crop needs by varying application rates and timing between blocks, guided by soil tests, crop class, cane variety, soil type, block history, soil conditioners and yield ...
Department of Agriculture and Fisheries, Queensland
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Applicability of ABR Service to Internet Applications [PDF]

open access: yes, 2000
Many studies on the performance of the ABR service category have been done. Most of these were simulation studies, and most evaluated performance only in the ATM layer. However, simulations do not provide a complete picture of how ABR service is used by actual applications running on existing networks.
openaire   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Web application obfuscation : -/WAFs. Evasion. Filters//alert (/Obfuscation/)- /

open access: yes, 2011
Web applications are used every day by millions of users, which is why they are one of the most popular vectors for attackers. Obfuscation of code has allowed hackers to take one attack and create hundreds-if not millions-of variants that can evade your ...
Heiderich, Mario.
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Conceptual Model of User Adaptive Enterprise Application

open access: yes
The user adaptive enterprise application is a software system, which adapts its behavior to an individual user on the basis of nontrivial inferences from information about the user.
Grabis, Jānis, Šūpulniece, Inese
core  

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