Results 151 to 160 of about 2,303,351 (296)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

CYCLODEXTRINS AND THEIR APPLICATION IN PHARMACEUTICAL INDUSTRY (REVIEW)

open access: yesРазработка и регистрация лекарственных средств, 2019
In the review describes the main properties of cyclodextrins and their potential use in the formulations in various dosage forms as excipients, by which it becomes possible to modify the solubility of drugs, increase the bioavailability and stability of ...
S. A. Kedik   +3 more
doaj  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Review of Balanced Scorecard Application in Public Hospital Setting

open access: yes
The purpose of this study is to review the empirical studies that have discussed the balanced scorecard in public hospital setting to determine the po-tential future research opportunities.
Sands, John, Khalid, Salim Khaleel
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Reassessment of the Application of TQM in the Public Sector

open access: yes, 2014
Numerous articles have been written regarding the application of TQM in the public sector. The purpose of this article is to delve into the roots of and to assess TQM, past and present, within the framework of public administration theory, and to ...
Maram, Allan
core  

Resiliency of forecasting methods in different application areas of smart grids: A review and future prospects

open access: yes
The cyber–physical infrastructure of a smart grid requires data-dependent artificial intelligence (AI)-based forecasting schemes for predicting different aspects for the short- to long-term, where AI-based schemes include machine learning (ML), deep ...
Rahman, M.A.   +11 more
core   +1 more source

Geopolymer Ceramic Application: A Review on Mix Design, Properties and Reinforcement Enhancement. [PDF]

open access: yesMaterials (Basel), 2022
Mohd Mortar NA   +9 more
europepmc   +1 more source

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