Results 161 to 170 of about 7,641,664 (271)

Anion Exchange Membranes for Fuel Cell Application: A Review. [PDF]

Polymers (Basel), 2022
Das G, Choi JH, Nguyen PKT, Kim DJ, Yoon YS.   +4 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Astaxanthin Delivery Systems for Skin Application: A Review. [PDF]

Mar Drugs, 2021
Lima SGM, Freire MCLC, Oliveira VDS, Solisio C, Converti A, de Lima ÁAN.   +5 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Impact of lactylation on the pathogenesis of cancer and its clinical application potential (Review). [PDF]

Mol Med Rep
Wang X, Chen J, Wang B, Li Y, Zhou X, Song Y, Miao C, Huang Y.   +7 more
europepmc   +1 more source

Mesenchymal Stem Cell Secretome for Dermatology Application: A Review. [PDF]

Clin Cosmet Investig Dermatol, 2021
Damayanti RH, Rusdiana T, Wathoni N.
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Research and practice progress of pulmonary rehabilitation in China and America

Huli yanjiu, 2020
WANG Tianjiao
doaj  

From back table innovation to contemporary application: a review of the frozen elephant trunk technique. [PDF]

Ann Cardiothorac Surg
Weiss G, Arnold Z, Folkmann S, Aschacher T, Tauber S, Harrer ML, Winkler B, Stabernak J, Gorlitzer M, Grabenwöger M.   +9 more
europepmc   +1 more source

Artificial Compound Eye Systems and Their Application: A Review. [PDF]

Micromachines (Basel), 2021
Phan HL, Phan HL, Yi J, Bae J, Ko H, Lee S, Cho D, Seo JM, Koo KI.   +8 more
europepmc   +1 more source