Results 251 to 260 of about 2,303,351 (296)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Reviewer Application

Heart & Lung, 2010
openaire   +2 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

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GWO: a review and applications

International Journal of System Assurance Engineering and Management, 2020
From the solitudinarian era to the present, the human race has been striving towards the betterment of his life by trying to find out the hidden secrets of our nature. Some time back one would hardly think that colonies of ant, pack of grey wolves, and elephants would be used to design an optimization algorithm.
Ganga Negi, Anuj Kumar, Sangeeta Pant, Mangey Ram   +3 more
openaire   +1 more source

Metaheuristics: review and application

Journal of Experimental & Theoretical Artificial Intelligence, 2013
The area of metaheuristics has grown immensely in the past two decades as a solution to real-world optimisation problems. They are able to perform well in situations where exact optimisation techniques fail to deliver satisfactory results. For complex optimisation problems (Nondeterministic polynomial time-hard problems), metaheuristic techniques are ...
Anupriya Gogna, Akash Tayal
openaire   +1 more source

Monoolein: A Review of the Pharmaceutical Applications

Drug Development and Industrial Pharmacy, 2000
Although monoolein is a well-known molecule commonly used as an emulsifying agent and as a food additive since the 1950s, its potential applicability in the pharmaceutical industry has not been con...
Ganem-Quintanar, Adriana, Quintanar-Guerrero, David, Buri, Pierre   +2 more
openaire   +3 more sources

Applications Reviews

Interfaces, 1981
An overview of recent articles from Growth and Change, Decision Sciences (AIDS), Management Science, MIS Quarterly (SMIS/MISRC), Operations Research, Policy Analysis, Policy Sciences, Regional Science and Urban Economics, and Socio-Economic Planning Sciences.
Roger N. Millen, John R. Hall, Vicki L. Sauter   +2 more
openaire   +1 more source

Applications Reviews

Interfaces, 1983
“Applications Reviews” is a guide to accomplished or partial MS/OR applications, cited in articles appearing in many of the major journals of the field. We cover only applications—except for the occasional brief mention of a survey article or special issue—and so do not claim to cover all the best articles in MS/OR.
John R. Hall, Roger N. Millen, Vicki L. Sauter, Russell S. Winer   +3 more
openaire   +1 more source