Results 41 to 50 of about 203,287 (216)
Fractal and Fractional, 2023 Given the intricate nature of contemporary energy systems, addressing the control and stability analysis of these systems necessitates the consideration of highly large-scale models. Transient stability analysis stands as a crucial challenge in enhancing
Arman Fathollahi, Björn Andresen
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
ADAPTIVE DECISION SUPPORT SYSTEMS FOR CYBER SECURITY
Сучасні інформаційні системи, 2019 The subject of the research is the principles and models of adaptive decision support systems in cyber security. The purpose is to develop basic principles and models underlying the operation of adaptive decision support systems in the field of ...
Oleksandr Milov
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
MODELING HETEROGENEOUS ENVIRONMENT AND MOBILE OBJECTS SUPERVISION IN MONITORING PROBLEMS
Informatika, 2016 A variant of monitoring problem formalization on the basis of the decision theory is considered. The models of heterogeneous environment and mobile heterogeneous object are offered as a structuralinformative basis for solving typical monitoring tasks ...
A. I. Kuzmich, V. V. Krasnoproshin
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Efficient Wheel-Rail Stick-Slip Numerical Modeling for Railway Traction Vehicles
Applied SciencesMotor railway vehicles necessitate enhanced control of wheel-rail contact mechanics to ensure optimal adhesion. During train running, driving wheelsets exhibit torsional vibrations that compromise adhesion and potentially lead to axle damage ...
Razvan Andrei Oprea +2 more
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Inferring reaction network structure from single-cell, multiplex data, using toric systems theory.
PLoS Computational Biology, 2019 The goal of many single-cell studies on eukaryotic cells is to gain insight into the biochemical reactions that control cell fate and state. In this paper we introduce the concept of Effective Stoichiometric Spaces (ESS) to guide the reconstruction of ...
Shu Wang +3 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source