Results 51 to 60 of about 201,713 (268)
Fractal and Fractional, 2023 Given the intricate nature of contemporary energy systems, addressing the control and stability analysis of these systems necessitates the consideration of highly large-scale models. Transient stability analysis stands as a crucial challenge in enhancing
Arman Fathollahi, Björn Andresen
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Solutions and Optimal Control of HIV-1 Dynamic Evolution Models
Taiyuan Ligong Daxue xuebao[Purposes] On the basis of the background and application of HIV-1 dynamic evolution models, in this paper, a kind of fractional HIV-1 dynamic evolution model involving control terms is investigated.
ZHOU Bibo +3 more
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
ADAPTIVE DECISION SUPPORT SYSTEMS FOR CYBER SECURITY
Сучасні інформаційні системи, 2019 The subject of the research is the principles and models of adaptive decision support systems in cyber security. The purpose is to develop basic principles and models underlying the operation of adaptive decision support systems in the field of ...
Oleksandr Milov
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
MODELING HETEROGENEOUS ENVIRONMENT AND MOBILE OBJECTS SUPERVISION IN MONITORING PROBLEMS
Informatika, 2016 A variant of monitoring problem formalization on the basis of the decision theory is considered. The models of heterogeneous environment and mobile heterogeneous object are offered as a structuralinformative basis for solving typical monitoring tasks ...
A. I. Kuzmich, V. V. Krasnoproshin
doaj
Efficient Wheel-Rail Stick-Slip Numerical Modeling for Railway Traction Vehicles
Applied SciencesMotor railway vehicles necessitate enhanced control of wheel-rail contact mechanics to ensure optimal adhesion. During train running, driving wheelsets exhibit torsional vibrations that compromise adhesion and potentially lead to axle damage ...
Razvan Andrei Oprea +2 more
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