Results 101 to 110 of about 1,750,780 (310)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Machine learning based prognostic model and mobile application software platform for predicting infection susceptibility of COVID-19 using healthcare data [PDF]

Research on Biomedical Engineering, 2020
Srivatsan R, Indi P, Agrahari S, Menon S, Ashok S.   +4 more
europepmc   +3 more sources

Outcome of visuospatial dysfunction assessment in patients with Parkinson's disease using mobile application software. [PDF]

Front Aging Neurosci, 2023
Shao X, Wang K, Zhang Y, Zhen X, Dong F, Tian H, Yu Y.   +6 more
europepmc   +1 more source

Software Components for Application Development [PDF]

, 2001
In this paper we discuss the needs of the application developer in terms of the components and tools required within an application development environment. We use, as examples, three European projects in which NAG has been a collaborator.
Arnaud Desitter, Antoine Le Hyaric, Geoff Morgan, Gareth Shaw, Anne E. Trefethen   +4 more
openaire   +1 more source

Domain-specific Design of Patient Classification in Cancer-Related Cachexia Research [PDF]

, 2018
We apply an IDE for user-level process design and composition to a real-life case study: a complex workflow from an ongoing global cancer-related cachexia research project.
Wickert, Alexander, Margaria, Tiziana, Anna-Lena Lamprecht, Alexander Wickert, Tiziana Margaria, Software Technology, Lamprecht, A.L., Sub Software Technology   +7 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Design and implementation of a model of migration from proprietary software to free software and application of open source technologies for educational institutions in the department of Chocó [PDF]

, 2009
El proyecto DISEÑO E IMPLEMENTACIÓN DE UN MODELO DE MIGRACIÓN DE SOFTWARE PROPIETARIO A SOFTWARE LIBRE Y APLICACIÓN DE TECNOLOGÍAS DE CÓDIGO ABIERTO PARA LAS INSTITUCIONES EDUCATIVAS DEL DEPARTAMENTO DEL CHOCÓ está orientado a obtener un conocimiento ...
Mena Palacios, José Faustin, Abuhatab Caicedo, Epifanio, Torres Arenas, Eduardo Antonio   +2 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Economic Complexity Based Recommendation Enhance the Efficiency of the Belt and Road Initiative

Entropy, 2018
The Belt and Road initiative (BRI) was announced in 2013 by the Chinese government. Its goal is to promote the cooperation between European and Asian countries, as well as enhancing the trust between members and unifying the market.
Hao Liao, Xiao-Min Huang, Alexandre Vidmer, Yi-Cheng Zhang, Ming-Yang Zhou   +4 more
doaj   +1 more source

Inter- and intra-rater reliability of new application software for computerised paediatric version of Wisconsin Gait Scale. [PDF]

Sci Rep, 2023
Guzik A, Wolan-Nieroda A, Drużbicki M.
europepmc   +1 more source