Results 41 to 50 of about 10,678,194 (257)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Performance evaluation and artificial neural network based thermal modelling of multi tilted active tiles in data centres

The Journal of Engineering, 2021
The main purpose of this paper is to improve the resilience of data center cooling system and reduce the energy consumption in data center by using the Tilted Active Tile (TATs).
Zeeshan Rasheed, Zhiyan Zhao, Gaoxiang Cong, Jianxiong Wan, Leixiao Li, Zhiqiang Ma   +5 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

GTWCLQ Software

, 2021
This software was developed to support computation of the geographically and temporally weighted co-location quotient (GTWCLQ).
Jianquan Cheng (11415272), Ling Li (11404097), Xiongfa Mai (11415273)   +2 more
core   +2 more sources

Does Software Modernization Deliver What It Aimed for?: A Post Modernization Analysis of Five Software Modernization Case Studies [PDF]

, 2015
Software modernization has been extensively researched, primarily focusing on observing the associated phenomena, and providing technical solutions to facilitate the modernization process.
Klein, Bart, Shrestra, Prajan, Shrestha, P., Prajan Shrestha, Bart Klein, Sub Software Production, Khadka, R., Slinger Jansen, Saeidi, A., Magiel Bruntink, Hage, J.; id_orcid, Jansen, S., Saeidi, Amir, Jansen, R.L., van Dis, E., Software Technology, Sub Software Technology, Sub Algemeen Software Systems, Bruntink, M., Khadka, Ravi, Jansen, Slinger, Ravi Khadka, Jurriaan Hage, Software Production, Hage, J., Dis, Edwin van, Klein, B., Edwin van Dis, Bruntink, Magiel, Saeidi, A.M., Amir Saeidi   +30 more
core   +2 more sources

Software Download

, 2022
Software ...
Myoungkyu Song (14179850)
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Checklist for a Software Management Plan

, 2016
It is easy to concentrate on short-term issues when developing research software. Getting publications, collaboration with others and the demands of a daily research routine can all conspire to prevent proper planning for the development of research ...
The Software Sustainability Institute
core   +1 more source