Results 71 to 80 of about 10,678,194 (257)
Method for predicting the reliability of applied software at the early stages of their development
Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019 To predict the expected reliability of the developed software applications, a method based on the use of the statistical model of the operability of software is proposed.
S. M. Borovikov +2 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
, 2021 Context: Exploiting software development related data from software-development intensive organizations to support tactical and strategic decision making is a challenge.
Abherve, Antonin, +5 more
core +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
AutoSpearman: Automatically Mitigating Correlated Software Metrics for Interpreting Defect Models
, 2018 The following topics are dealt with: software maintenance; public domain software; software engineering; program debugging; program testing; Java; mobile computing; application program interfaces; pattern classification; Android (operating system ...
Christoph Treude +8 more
core +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
, 2017 A multi-agent-based software system for modelling and simulation of the value space of low carbon dioxide emission ...
Li, Shuliang, Zeng, Y.
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Data Science JournalResearch data management (RDM) is key to fast and effective cooperation in collaborative research projects, especially when several scientific disciplines are involved.
Marlene Pacharra +2 more
doaj +1 more source