Results 241 to 250 of about 6,175,713 (309)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Technology application notes

open access: yes
Optimized protocols and technology application notes for:a) Use of mid-range IR profiling in plasma to find NAFLD/NASH specific signatures which can be used for diagnostics.b) Detection of markers of liver necroptosis or miRNA in plasma through specific detection kits.
openaire   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Digital Pain Assessment: Patient and Family Perspectives. [PDF]

open access: yesNurs Rep
Saunders R   +15 more
europepmc   +1 more source

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