Results 81 to 90 of about 6,175,713 (309)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Application technology to fight the COVID-19 pandemic: Lessons learned in Thailand. [PDF]
Biochem Biophys Res Commun, 2021 Intawong K, Olson D, Chariyalertsak S.
europepmc +2 more sources
SUBSTANTIATION INTO PRACTICAL APPLICATION OF THE BIOMASS GASIFICATION TECHNOLOGY [PDF]
, 2018 Consumption of energy resources in the nearest time will provoke their rapid rise, accompanied by their gradual exhaustion. This situation requires a search of internal reserves based on renewable energy.
LOZYNSKA, Diana +5 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Planta Daninha, 2009 Este estudo teve por objetivo avaliar a ação de adjuvantes na absorção e translocação de glyphosate em plantas de aguapé (Eichhornia crassipes). Os tratamentos foram dispostos em esquema fatorial 5 x 8, sendo: cinco tratamentos com glyphosate (sem ...
D. Martins +3 more
doaj +1 more source
Identity theft hits the UK [PDF]
, 2006 Bruce Grant-Braham examines the latest hospitality information technology ...
Grant-Braham, Bruce
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Engenharia Agrícola, 2010 Os avanços da tecnologia de aplicação aérea de agroquímicos têm-se dado na direção de redução do volume de calda, o que pode ocasionar má distribuição e consequente deposição irregular.
Elton F. dos Reis +3 more
doaj +1 more source
The top 5 link building strategies for hospitality managers [PDF]
, 2009 Bruce Grant-Braham examines the latest hospitality information technology ...
Grant-Braham, Bruce
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source