Results 31 to 40 of about 63,555 (259)
The complexity of two graph orientation problems
, 2012 This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2012 ElsevierWe consider two orientation problems in a graph, namely the minimization of the sum of all the shortest path ...
Noble, Steven D. +7 more
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Graph Theory and Mean Shift Segmentation Based Classification of Building Facades
, 2011 Automatic classification of building facades has become a field of interest for researchers, since it can provide important solutions to many remote sensing research field.
Sirmacek, Beril, Beril Sirmacek
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A graph rewriting programming language for graph drawing [PDF]
, 1998 This paper describes Grrr, a prototype visual graph drawing tool. Previously there were no visual languages for programming graph drawing algorithms despite the inherently visual nature of the process.
Rodgers, Peter
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The Configuration Space of Two Particles Moving on a Graph [PDF]
, 2010 In this thesis we study the configuration space, F (Γ, 2), of two particles moving without collisions on a graph Γ with a view to calculating the Betti numbers of this space. We develop an intersection theory for cycles in graphs inspired by the classical
BARNETT, KATHRYN
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Maximal Planar Graph Theory and the Four-Color Conjecture
This open access book integrates foundational principles with advanced methodologies concerning maximal planar graphs. It offers readers an exceptional examination of graph structures, chromatic polynomials, and the construction and proof techniques of ...
Xu, Jin
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