Results 41 to 50 of about 63,555 (259)

Problems on chromatic polynomials of hypergraphs

open access: yes, 2020
Chromatic polynomials of graphs have been studied extensively for around one century. The concept of chromatic polynomial of a hypergraph is a natural extension of chromatic polynomial of a graph. It also has been studied for more than 30 years.
Ruixue Zhang   +3 more
core   +1 more source

List graphs and distance-consistent node labelings [PDF]

open access: yes, 2018
In this paper we consider node labelings c of an undirected connected graph G = (V, E) with labels {1, 2, ..., ∣V∣}, which induce a list distance c(u, v) = ∣c(v) − c(u)∣ besides the usual graph distance d(u, v).
Eriksson, Mattias,   +5 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Graph Homomorphism Revisited for Graph Matching

open access: yes, 2010
In a variety of emerging applications one needs to decide whether a graph G matches another Gp, i.e., whether G has a topological structure similar to that of Gp. The traditional notions of graph homomorphism and isomorphism often fall short of capturing
Li, Jianzhong   +4 more
core  

Rectilinear approximation and volume estimates for hereditary bodies via [0,1]-decorated containers

open access: yes, 2023
We use the hypergraph container theory of Balogh--Morris--Samotij and Saxton--Thomason to obtain general rectilinear approximations and volume estimates for sequences of bodies closed under certain families of projections.
Andrew Uzzell   +10 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Errata: New measures of graph irregularity

open access: yes, 2015
This paper gives an errata to the paper "New measure of graph irregularity", Electronic Journal of Graph Theory and Applications {\bf 2}(1) (2014), 52 ...
Pawel Wocjan, Clive Elphick
core   +1 more source

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