Results 51 to 60 of about 54,702 (261)

A Hybrid Floyd-Warshall and Graph Coloring Algorithm for Finding the Smallest Number of Colors Needed for a Distance Coloring of Graphs [PDF]

Control and Optimization in Applied Mathematics
Graph coloring is a crucial area of research in graph theory, with numerous algorithms proposed for various types of graph coloring, particularly graph p-distance coloring.
Hanifa Mosawi, Mostafa Tavakolli, Khatere Ghorbani-Moghadam   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Fault-Tolerant Partition Resolvability of Cyclic Networks

Journal of Mathematics, 2021
Graph invariants provide an amazing tool to analyze the abstract structures of networks. The interaction and interconnection between devices, sensors, and service providers have opened the door for an eruption of mobile over the web applications ...
Kamran Azhar, Sohail Zafar, Agha Kashif, Michael Onyango Ojiema   +3 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

On topological indices and entropy measures of beryllonitrene network via logarithmic regression model

Scientific Reports
Chemical graph theory, a subfield of graph theory, is used to investigate chemical substances and their characteristics. Chemical graph analysis sheds light on the connection, symmetry, and reactivity of molecules.
Guofeng Yu, Muhammad Kamran Siddiqui, Mazhar Hussain, Nazir Hussain, Zohaib Saddique, Fikre Bogale Petros   +5 more
doaj   +1 more source

The development of e-learning applications solving problems from graph theory

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2013
Authors are in long term developing e-learning supports for some parts of Operation Research course. The original purpose was to prepare e-learning supports for students of FBE Mendelu, mainly for part-time form students, who have subscribed Economic ...
Pavel Kolman, Petr Zach, Josef Holoubek
doaj   +1 more source

On applications of bipartite graph associated with algebraic structures

Open Mathematics, 2020
The latest developments in algebra and graph theory allow us to ask a natural question, what is the application in real world of this graph associated with some mathematical system? Groups can be used to construct new non-associative algebraic structures,
Zhang Xiujun, Nadeem Muhammed, Ahmad Sarfraz, Siddiqui Muhammad Kamran   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source