Results 121 to 130 of about 41,148 (275)

USB1 deficiency disrupts neutrophil maturation via RNA dysregulation independent of global pre‐mRNA splicing

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the essential role of USB1 in neutrophil maturation. In normal myeloid cells, USB1 acts as an RNA exonuclease, trimming RNA tails to maintain proper RNA network function, which supports the differentiation of myeloid progenitor cells into mature neutrophils.
Hang Li, Guiying Shi, Jiaming Tang, Yiying Huang, Jie Wang, Xuepei Lei, Lin Bai   +6 more
wiley   +1 more source

MiR‐30a‐5p mediates epileptogenesis in epilepsy models by targeting SOX4 to regulate the Wnt/β‐catenin pathway

Epilepsia Open, EarlyView.
Abstract Objective The pathogenesis of epilepsy is closely associated with neuronal synaptic plasticity. MicroRNAs (miRNAs) can regulate various biological processes by binding to specific sequences on target genes. This study employs bioinformatics, molecular dynamics, and experimental approaches to investigate the mechanism by which MiR‐30a‐5p treats
Zhenlin Yang, Xu Zhang, Jingjing Guo, Yuanxin Wei, Jinzi Li   +4 more
wiley   +1 more source

Expressions for some hypergeometric functions of matrix argument with applications

Journal of Multivariate Analysis, 1975
AbstractReasonably simple expressions are given for some hypergeometric functions when the size of the argument matrix or matrices is two. Applications of these expressions in connection with the distributions of the latent roots of a 2 × 2 Wishart matrix are also given.
openaire   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

On the expansion of the Kummer function in terms of incomplete Gamma functions

, 2003
The expansion of Kummer's hypergeometric function as a series of incomplete Gamma functions is discussed, for real values of the parameters and of the variable.
Morosi, Carlo, Pizzocchero, Livio
core  

Alternative Price Dynamics and Valuation of Flexible Strategies

International Journal of Finance &Economics, EarlyView.
ABSTRACT In this article, we study the optimal operational strategy of production projects. We investigate different underlying price models and determine the optimal barriers of transition to suspension, recovery, or irreversible abandonment of productive activity.
Cristina Bertolosi, Gianluca Fusai, Ioannis Kyriakou   +2 more
wiley   +1 more source

Monocytes with trained immunity–like signatures are associated with acute anterior uveitis in ankylosing spondylitis

Interdisciplinary Medicine, EarlyView.
In ankylosing spondylitis‐acute anterior uveitis (AS‐AAU), trained immunity monocytes (Mono‐TI) differentiate into macrophages in the eye, retaining trained immunity features. Mono‐TI cells secrete pro‐inflammatory cytokines and chemokines, including IL‐1β, TNF‐α, and CCL3.
Yimeng Sun, Lu Zhang, Xinyu Yao, Yunfei Liu, Xin Li, Feng Wen, Yong Dai, Ye Dai, Ziyu Du, Dijie Qiao, Ziwei Meng, Cong Hu, Chun Yan, Wei Chi   +13 more
wiley   +1 more source

A highly accurate numerical method for solving boundary value problem of generalized Bagley‐Torvik equation

Mathematical Methods in the Applied Sciences, EarlyView.
A highly accurate numerical method is given for the solution of boundary value problem of generalized Bagley‐Torvik (BgT) equation with Caputo derivative of order 0<β<2$$ 0<\beta <2 $$ by using the collocation‐shooting method (C‐SM). The collocation solution is constructed in the space Sm+1(1)$$ {S}_{m+1}^{(1)} $$ as piecewise polynomials of degree at ...
Suzan Cival Buranay, Mtema James Chin, Nazim I. Mahmudov   +2 more
wiley   +1 more source

A New Double Weighted Fuzzy Hypergeometric Naive Bayes Network and its Application for User’s Assessment in Virtual Reality Simulators

International Journal of Computational Intelligence Systems
Assessment methods have been used for identify the quality of procedures performed by human beings. In virtual reality simulators, user’s interaction data can be collected and utilized by Single User Assessment Systems (SUAS) to assess the user’s ...
Jodavid Ferreira, Liliane S. Machado, Ronei Marcos de Moraes   +2 more
doaj   +1 more source

Finite Biorthogonal Polynomials Suggested by the Finite Orthogonal Polynomials Mnp,qx$$ {M}_n^{\left(p,q\right)}(x) $$

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT Constructing a biorthogonal structure from scratch, that is, defining a biorthogonal pair is quite tough. Because here the orthogonality must be established between two different sets. There are four known univariate biorthogonal polynomial sets, suggested by Laguerre, Jacobi, Hermite and Szegő‐Hermite polynomials, in the literature.
Esra Güldoğan Lekesiz
wiley   +1 more source