Results 111 to 120 of about 41,148 (275)

SERRATE Regulates Floral Meristem Activity by Antagonizing SHOOT MERISTEMLESS and Repressing Cytokinin Signaling

open access: yesAdvanced Science, EarlyView.
Floral meristem (FM) activity is crucial for the initiation of floral organs. In this study, SE represses IPT7 expression and cytokinin signaling via both the miR171c‐5p–KNAT2 and miR164c–CUC1/2–KNAT2 regulatory modules, thereby repressing FM activity. In contrast, STM induces both KNAT2 and IPT7 expression.
Wen Yang   +11 more
wiley   +1 more source

G6PC Downregulation Promotes Renal Calcium Oxalate Stone Formation via Lactate‐Induced SNAIL1 K206 Lactylation and Epithelial‐Mesenchymal Transition

open access: yesAdvanced Science, EarlyView.
In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...
Kai Liu   +16 more
wiley   +1 more source

EVALUATION OF SOME NON-ELEMENTARY INTEGRALS INVOLVING SINE, COSINE, EXPONENTIAL AND LOGARITHMIC INTEGRALS: PART I

open access: yesUral Mathematical Journal, 2018
The non-elementary integrals \(\text{Si}_{\beta,\alpha}=\int [\sin{(\lambda x^\beta)}/(\lambda x^\alpha)] dx,\)  \(\beta\ge1,\) \(\alpha\le\beta+1\) and \(\text{Ci}_{\beta,\alpha}=\int [\cos{(\lambda x^\beta)}/(\lambda x^\alpha)] dx,\) \(\beta\ge1 ...
Victor Nijimbere
doaj   +1 more source

STAID: A Self‐Refining Deep Learning Framework for Spatial Cell‐Type Deconvolution with Biologically Informed Modeling

open access: yesAdvanced Science, EarlyView.
STAID is a unified deep learning framework that couples iterative pseudo‐spot refinement with neural network training through a feedback loop and exploits gene co‐expression information to model higher‐order interactions, achieving accurate and robust cell‐type deconvolution in spatial transcriptomics.
Jixin Liu   +5 more
wiley   +1 more source

A Class of Extended Hypergeometric Functions and Its Applications

open access: yes, 2013
Recently, there emerges different versions of beta function and hypergeometric functions containing extra parameters. Gaining enlightenment from these ideas, we will first introduce a new extension of generalized hypergeometric function and then put forward some fundamental results in the paper. Next, we will derive some properties of certain functions
openaire   +2 more sources

Dissecting Pirtobrutinib Resistance in Mantle Cell Lymphoma Through Single‐Cell Multi‐Omics

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Pirtobrutinib (PBN), a non‐covalent BTK inhibitor, has been approved by the FDA for relapsed/refractory mantle cell lymphoma (MCL); however, resistance to PBN has been observed. To dissect the molecular dynamics driving PBN resistance, we performed integrative single‐cell multi‐omic profiling (scRNA‐seq, scATAC‐seq, and scDNA‐seq) on ...
Fangfang Yan   +10 more
wiley   +1 more source

On a class of generalized analytic functions

open access: yesLe Matematiche, 2012
This paper deals with a new generalization of analytical functions.The p-wave functions are introduced and studied. We consider their theoretical aspect and applications. Some integral representations of x^k y^l -wave functions (k, l − const.
Shyam L. Kalla   +2 more
doaj  

A Review of Certain Modern Special Functions and Their Applications

open access: yesAbstract and Applied Analysis
This review article comprehensively analyzes recent developments in the generalization of special functions (SFs) and polynomials via various fractional calculus operators (FCOs), focusing on the analytical properties and applications of extended Hurwitz–
Hala Abd Elmageed, Mohamed Abdalla
doaj   +1 more source

SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang   +6 more
wiley   +1 more source

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