Results 91 to 100 of about 41,148 (275)

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

Hadamard k-fractional inequalities of Fejér type for GA-s-convex mappings and applications

Journal of Inequalities and Applications, 2019
The main aim of this paper is to establish some Fejér-type inequalities involving hypergeometric functions in terms of GA-s-convexity. For this purpose, we construct a Hadamard k-fractional identity related to geometrically symmetric mappings.
Hui Lei, Gou Hu, Zhi-Jie Cao, Ting-Song Du   +3 more
doaj   +1 more source

On the Generalized Confluent Hypergeometric Function and Its Application [PDF]

, 2006
2000 Mathematics Subject Classification: 26A33, 33C20This paper is devoted to further development of important case of Wright’s hypergeometric function and its applications to the generalization of Γ-, B-, ψ-, ζ-, Volterra ...
Virchenko, Nina
core  

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

Transformation and Summation Formulas for Exton's Functions K11, K14 And K15

مجلّة جامعة عدن للعلوم الأساسيّة والتّطبيقيّة, 2020
The aim of the present paper is to establish some transformation formulas for Exton's quadruple hypergeometric functions K11, K14 and K15. Several summation formulas for K11, K14 and K15 are also derived as an applications of our main results with the ...
Ahmed Ali Atash, Hussein Saleh Bellehaj
doaj  

Fractional order of Legendre-type matrix polynomials

Advances in Difference Equations, 2020
Recently, special functions of fractional order calculus have had many applications in various areas of mathematical analysis, physics, probability theory, optimization theory, graph theory, control systems, earth sciences, and engineering. Very recently,
M. Zayed, M. Hidan, M. Abdalla, M. Abul-Ez   +3 more
doaj   +1 more source

Integrating Radiomics and Computational Pathology to Predict Early Recurrence of Pancreatic Ductal Adenocarcinoma and Uncover Its Biological Basis in Tumor Microenvironment

Advanced Science, EarlyView.
Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng, Fuze Cong, Shenbo Zhang, Rui Lv, Wenjia Zhang, Xinyi Ke, Juncheng Wu, Zhonghe Zhao, Kui Zhao, Di Dong, Ruofan Zhang, Zhengyu Jin, Max Seidensticker, Zhiwei Wang, Huanwen Wu, Xianlin Han, Nan Hong, Huadan Xue   +17 more
wiley   +1 more source

Derivatives of continued fractions with applications to hypergeometric functions

Journal of Computational and Applied Mathematics, 1987
The purpose of the present paper is to illustrate the method on regular C-fraction expansions for certain hypergeometric functions. The emphasis is on developing the formulas needed. Numerical examples are indicated in some special cases.
openaire   +1 more source

Smartly Assembled near‐Micron RF‐Responsive Agents Bridge Transarterial Embolization and Immunothermal Potentiation

Advanced Science, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) remains a significant clinical challenge due to the limited efficacy of conventional treatments like surgery, radiofrequency ablation (RFA), and transarterial embolization (TAE). Here, we develop an innovative TAE and immunothermal therapy strategy based on smartly assembled near‐micron layered double hydroxide ...
Qitao Hu, Junkang Ding, Lingxiao Zhang, Zhou Tian, Cheng Zeng, Shaomin Zou, Wenjing Zhang, Tangye Zeng, Zhencang Gao, Zhouyi Sun, Gang Liu, Weiyu Chen, Zhe Tang   +12 more
wiley   +1 more source