Results 161 to 170 of about 40,939 (252)

Analytic study and statistical enforcement of extended beta functions imposed by Mittag-Leffler and Hurwitz-Lerch Zeta functions. [PDF]

MethodsX
Abdulnabi FF, Al-Janaby HF, Ghanim F.
europepmc   +1 more source

A tissue‐resolved, network‐based transcriptomic framework for abiotic stress responses in sorghum

The Plant Journal, Volume 126, Issue 1, April 2026.
SUMMARY Developing climate‐resilient crops requires a detailed understanding of stress‐induced gene expression dynamics, as maladaptive responses can compromise their productivity and survival. Sorghum, a globally important cereal with exceptional tolerance to multiple abiotic stresses, provides a powerful system for investigating these dynamics ...
Dae Kwan Ko, Federica Brandizzi
wiley   +1 more source

Any Topological Recursion on a Rational Spectral Curve is KP Integrable. [PDF]

Commun Math Phys
Alexandrov A, Bychkov B, Dunin-Barkowski P, Kazarian M, Shadrin S.   +4 more
europepmc   +1 more source

Wnt Signaling Downregulation Mediates T Cell Apoptosis Following OKT3‐Induced T Cell Activation in Preclinical Models

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
In OKT3‐treated human PBMCs, Wnt signaling was downregulated, and co‐treatment with the Wnt activator CHIR99021 reduced T cell activation and apoptosis. In humanized mice, transcriptomic profiling revealed upregulation of genes associated with T cell activation, cytokine and ROS production, and apoptosis, with downregulation of canonical Wnt signaling.
Myeongjin Choi, Duhyeon Park, Da‐Hee Lee, Chang Hoon Choi, Minseong Jo, Seo Yule Jeong, Seung Yeon Lim, Daeui Park, Kyoung‐Sik Moon   +8 more
wiley   +1 more source

The mirage of DNA methylation in transcriptional regulation of plants. [PDF]

Plant Genome
Civan P, Sammarco I, Banouh M.
europepmc   +1 more source

Diminazene Aceturate Ameliorates Hypertension‐Induced Cognitive Impairment by Disrupting the CCN1–Integrin αvβ6–TGF‐β Axis and Preserving Mitochondrial Integrity

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Hypertension drives cognitive decline through a previously unrecognized CCN1–integrin αvβ6–TGF‐β signaling axis that culminates in mitochondrial dysfunction and hippocampal neuronal injury. In this pathway, angiotensin II induces CCN1 upregulation, which activates αvβ6 integrin‐mediated release of latent TGF‐β, triggering SMAD2/3 phosphorylation and ...
Xufang Huo, Zhenyu Wu, Xinqian Zhou, Yuancheng Zhou, Jiming Liu, Hongbing Li, Yijiu Wu, You Huang, Guangling Feng, Xiaolin Hu, Qingfan Zeng   +10 more
wiley   +1 more source

Differential subordination and superordination results for p-valent analytic functions associated with (r,k)-Srivastava fractional integral calculus. [PDF]

MethodsX
Tayyah AS, Atshan WG.
europepmc   +1 more source

Single Cell Analysis Reveals the Presence of Novel Intermediate Cells in Both Mice and Patients With Severe MASLD

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Schematic overview of the experimental workflow combining single‐cell RNA sequencing and spatial proteomics in a murine model of MASLD. Tissues were isolated, dissociated, and processed for single‐cell transcriptomic profiling to identify distinct cellular clusters and define cell‐type–specific gene expression signatures. Computational analysis enabled
Marica Meroni, Paride Pelucchi, Erika Paolini, Miriam Longo, Ada Sula, Michele Battistin, Alice Chiodi, Deborah Mattinzoli, Masami Ikehata, Elena Trombetta, Daniele Dondossola, Alessandra Mezzelani, Gianluca Martino Tartaglia, Giuseppe Castellano, Anna Ludovica Fracanzani, Flora Peyvandi, Stefano Gatti, Ettore Mosca, Paola Dongiovanni   +18 more
wiley   +1 more source

CLinNET: An Interpretable and Uncertainty-Aware Deep Learning Framework for Multi-Modal Clinical Genomics. [PDF]

Adv Sci (Weinh)
Bakhshayeshi I, Hosseini MM, Argha A, Zahedi R, Lovell NH, Alinejad-Rokny H.   +5 more
europepmc   +1 more source

C‐X‐C chemokine receptor CXCR4 mediates diurnal changes in the aggregation and dispersion of CD8+ T cells within the tumor microenvironment

International Journal of Cancer, Volume 158, Issue 6, Page 1740-1754, 15 March 2026.
What's new? In addition to governing daily variations in biological activity, the circadian clock regulates immune cell migration into tumors. Whether this influence extends to immune cell localization within the tumor microenvironment (TME) is unknown. Here, using cell and animal models, the authors investigated immune cell distribution within the TME
Akito Tsuruta, Marina Fujimoto, Yasuha Hiraoka, Aoi Taniguchi, Yuki Shiiba, Takuto Inoki, Tomoaki Yamauchi, Yuya Yoshida, Naoya Matsunaga, Shigehiro Ohdo, Satoru Koyanagi   +10 more
wiley   +1 more source