Results 201 to 210 of about 41,148 (275)

Pharmacological inhibition of hydroxysteroid 11‐beta dehydrogenase type 1 (11‐βHSD1) after myocardial infarction preserves cardiac function in a translational mini‐pig model

British Journal of Pharmacology, Volume 183, Issue 10, Page 2236-2255, May 2026.
Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi, Raimondo Ascione, Shazia Khan, Thomas Johnson, Eva Sammut, Vito Domenico Bruno, Daniel Baz Lopez, Carol‐Anne James, Joanna Simpson, Natalie Z. Homer, Michael Millar, Trisha Singh, Alex von Kreigsheim, Nick L. Mills, Brian R. Walker, Ruth Andrew, Scott P. Webster, Andrew Whittaker, Adrian Freeman, Gillian A. Gray   +19 more
wiley   +1 more source

CooccurrenceAffinity: An R package for computing a novel metric of affinity in co-occurrence data that corrects for pervasive errors in traditional indices. [PDF]

PLoS One
Mainali KP, Slud E.
europepmc   +1 more source

Beyond Co‐Occurrence: Multi‐Scale Evidence for Segregation‐Dominated Plant Networks in the French Alps

Ecology Letters, Volume 29, Issue 5, May 2026.
Using high‐resolution spatial data and a multi‐scale statistical framework, we disentangle plant co‐occurrence from true spatial associations across alpine communities in the French Alps. We discovered that local species associations are dependent on soil acidity and nitrogen rather than temperature. By building a global network from these associations,
Matthias Rohr, Alexandre Wendling, Tamara Münkemüller, Dominique Gravel, Clovis Galiez, Julien Renaud, Orchamp Consortium, Wilfried Thuiller   +7 more
wiley   +1 more source

Low dose IFNγ remodels enhancer landscape to potentiate mesenchymal stromal cell activation. [PDF]

Stem Cell Res Ther
Lin J, Ruan D, Hu Q, Cao X, Zhou W, Hu S.   +5 more
europepmc   +1 more source

Different Paths, Similar Pressures: Divergent Drivers of Genetic Diversity Despite Convergent Genomic Signatures of Selection in Response to Urban Intensity in Two Oligolectic Bee Species

Molecular Ecology, Volume 35, Issue 9, May 2026.
ABSTRACT Urbanisation is a pervasive form of anthropogenic environmental change and a driver of contemporary evolution. Yet, it remains unclear how demographic processes and environmentally associated genomic variation shape genomic patterns in cities and whether these responses depend on species‐specific ecological traits.
Lucie M. Baltz, Hanna Gardein, Henri Greil, Robert J. Paxton, Panagiotis Theodorou   +4 more
wiley   +1 more source

Deciphering DEL pocket patterns through contrastive learning. [PDF]

Nat Commun
Zhang W, Wang Y, Zhan R, Qian R, Hu Q, Huang J.   +5 more
europepmc   +1 more source

Arabidopsis acclimation to daily environmental fluctuations converts a defense response regulator into a susceptibility factor toward Sclerotinia

New Phytologist, Volume 250, Issue 4, Page 2516-2534, May 2026.
Summary Acclimation enables plants to adjust to immediate environmental fluctuations and is therefore key to the resilience of plant disease resistance in a time of climate change. Here, we report on the acclimation of Arabidopsis thaliana quantitative immune responses against the fungal pathogen Sclerotinia sclerotiorum to daily environmental ...
Marie Didelon, Justine Sucher, Florent Delplace, Pedro Carvalho‐Silva, Matilda Zaffuto, Adelin Barbacci, Sylvain Raffaele   +6 more
wiley   +1 more source

Single-Molecule Peptide Discrimination via Flow-Through SERS and Machine Learning. [PDF]

ACS Photonics
Khabarov K, Baldi IM, Blanco Formoso M, Khozeymeh Sarbishe F, Storari V, Villa F, Difato F, Tantussi F, De Angelis F.   +8 more
europepmc   +1 more source

Mass Spectrometry Imaging Combined With Single‐Cell Transcriptional Profiling Reveals the Multidimensional Spatial Distributions and Biosynthetic Pathways of Medicinal Components in Andrographis paniculata

Plant Biotechnology Journal, Volume 24, Issue 5, Page 2876-2890, May 2026.
ABSTRACT The synthesis and accumulation of active ingredients in medicinal plants are distributed in specific organs, tissues, and cell types, which are important for the exploitation of medicinal plants. However, the fine distribution of active ingredients is difficult to know. Here, the system of mass spectrometry imaging (MSI) integrated with single‐
HaiSheng Zeng, MeiHui Shi, ZhiRong Chen, XueJing Sun, HuiJie Zhang, Yue Huang, YuCheng Chen, Jun Ren, HuiLing Huang, Almaz Borjigidai, Man Zhang, SuJuan Duan, Yi‐Jun Chen, Hong‐Lei Jin, Hong‐Bin Wang   +14 more
wiley   +1 more source

Hirota, Fay and geometry. [PDF]

Lett Math Phys
Eynard B, Oukassi S.
europepmc   +1 more source