Results 191 to 200 of about 41,148 (275)

Preterm Birth Increases Susceptibility to Hyperglycemia‐Induced Kidney Injury With Sex‐Specific Differences in Structural and Molecular Responses

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 3, May 2026.
Preterm mice were delivered at 19 dpc and rendered diabetic with STZ at 6 weeks; kidneys were analysed at 18 weeks. PT‐D females showed increased atubular glomeruli, reduced proximal tubule fraction, higher albuminuria and BUN, and dysregulated fibrotic, vascular, mitochondrial, and Notch pathways.
Rachel K. Dailey, Aleksandra Cwiek, Logan C. Hamil, Sage Timberline, Ayyappa Kumar Sista Kameshwar, Masako Suzuki, Jaya Isaac, Kimberly deRonde, Mark Conaway, Kevin M. Bennett, Edwin J. Baldelomar, Matthew R. Hoch, Kimberly J. Reidy, Jennifer R. Charlton   +13 more
wiley   +1 more source

On some integral inequalities of Grüss type involving the generalized fractional Saigo k-integral operator. [PDF]

Heliyon
Abbas A, Mubeen S, Khan A, Abdeljawad T.
europepmc   +1 more source

Proximity Labelling Reveals the Compartmental Proteome of Murine Sensory Neurons

European Journal of Pain, Volume 30, Issue 5, May 2026.
ABSTRACT Introduction Understanding the molecular architecture of peripheral sensory neurons is critical as we pursue novel drug targets against pain and neuropathy. Sensory neurons in the dorsal root ganglion (DRG) show extensive compartmentalization; thus, understanding each compartment—from the peripheral to central terminals—is key to this effort ...
Julia R. Sondermann, Allison M. Barry, Feng Xian, Thomas Haberl, David Gomez‐Varela, Fritz Benseler, Dietmar Schreiner, Nils Brose, Noa Lipstein, Manuela Schmidt   +9 more
wiley   +1 more source

Multi-omics analyses reveal regulatory networks underpinning metabolite biosynthesis in Nicotiana tabacum. [PDF]

Nat Commun
Li J, Liao Q, Zhou H, Hu R, Li Y, Hu Z, Yu B, Liu P, Zheng Q, Pu W, Sheng S, Liu Y, Wu S, Liu T, Xiao Q, Duan S, Gao J, Li X, Wang S, Xiao H, Zhou Z, Lu Z, Yang J, Yan J.   +23 more
europepmc   +1 more source

Astragaloside IV Reprograms Spatial Glycolytic Metabolism in Diabetic Kidney: A Microenvironment‐Targeted Immunometabolic Therapeutic Strategy

Food Frontiers, Volume 7, Issue 3, May 2026.
Diabetic nephropathy (DN) is driven by spatially organized immunometabolic dysfunction. Integrating high‐resolution spatial transcriptomics (10× Visium HD) and metabolomics (MALDI‐MSI), we mapped a pathogenic glycolytic blockade within diabetic kidney microenvironments.
Shi Qiu, Zhibo Wang, Sifan Guo, Dandan Xie, Ying Cai, Xian Wang, Yan Wang, Xiaodan Yu, Jinxuan Chai, Hong Yao, Chunsheng Lin, Qiang Yang, Yu Guan, Qiqi Zhao, Songqi Tang, Wenjie Sun, Yiqiang Xie, Aihua Zhang   +17 more
wiley   +1 more source

An Integrated Network Biology and Molecular Dynamics Approach Identifies CD44 as a Promising Therapeutic Target in Multiple Sclerosis. [PDF]

Pharmaceuticals (Basel)
Aljasir MA.
europepmc   +1 more source

From Power‐Law to Correlation‐Time Distributions: A Unified Framework for the Analysis of Nuclear Magnetic Relaxation Dispersion (NMRD) Profiles of Complex Biological Systems

Magnetic Resonance in Chemistry, Volume 64, Issue 5, Page 494-505, May 2026.
1H NMRD profiles of biological systems often follow a power‐law dependence rather than a Lorentzian dispersion. This behavior can arise from a broad distribution of correlation times, weighted by 1/τ 1−α. Validated across diverse systems such as sedimented proteins and biological tissues, this framework provides a physical interpretation of power‐law ...
Giacomo Parigi, Adam Kubrak
wiley   +1 more source

Impacts of host genetics on gut microbiome composition in Alzheimer's disease. [PDF]

Microbiome
Liu J, Cao J, Jia L, Gan Z, Zhao X, Yang A, Lai S, Chen F, Yang YT, Zhao XM.   +9 more
europepmc   +1 more source

Loss of Chromosome Y Associates With Altered Immune Cell Trajectories and X‐Inactivation Features

Aging Cell, Volume 25, Issue 5, May 2026.
Loss of chromosome Y in male leukocytes exhibits cell type‐specific effects on immune cell phenotypes and transcriptional profiles along differentiation trajectories. LOY is associated with profibrotic monocyte signatures and aberrant X‐inactivation gene expression, highlighting links to immune dysfunction and age‐related diseases in men.
Ahmed Dawoud, Luke Green, Owen Rackham
wiley   +1 more source

Kicked General Fractional Lorenz-Type Equations: Exact Solutions and Multi-Dimensional Discrete Maps. [PDF]

Entropy (Basel)
Tarasov VE.
europepmc   +1 more source