Results 211 to 220 of about 41,081 (281)
Aging Cell, Volume 25, Issue 2, February 2026.Assessment of oxygen consumption rates in young, middle‐aged, and old flies from the Drosophila B lines and long‐lived O lines revealed a significant increase in metabolic rate with aging only in B flies. Lisinopril prevented the age‐related rise in metabolic rate in B female flies.
Denise Vecchié +3 more
wiley +1 more source
ArGD: An Integrated Database and Analysis Platform for Artocarpus Genomics and Transcriptomics. [PDF]
Genes (Basel)Sun P, Xi H, Yang L, Chen L, Bao Y.
europepmc +1 more source
Aging Cell, Volume 25, Issue 2, February 2026.MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong +9 more
wiley +1 more source
Analysis and comparison of the bacterial σ54 regulon: Evidence of phylogenetic trends in gene regulation. [PDF]
PLoS OneCarrera-Reyna M +2 more
europepmc +1 more source
Rapamycin Reverses the Hepatic Response to Diet‐Induced Metabolic Stress That Is Amplified by Aging
Aging Cell, Volume 25, Issue 2, February 2026.Aging exacerbates high‐fat diet (HFD) induced hepatic steatosis, and transcriptional dysregulation of pathways including inflammation, immune, and metabolic regulation in mouse liver and hepatocytes. The addition of rapamycin to HFD reversed most HFD‐driven gene‐expression changes in old mice, including those linked to metabolic dysfunction and ...
Aaron Havas +11 more
wiley +1 more source
Convolution identities for divisor sums and modular forms. [PDF]
Proc Natl Acad Sci U S AFedosova K +2 more
europepmc +1 more source
Plasma Proteome Profiling of Centenarian Across Switzerland Reveals Key Youth‐Associated Proteins
Aging Cell, Volume 25, Issue 2, February 2026.We characterized the plasma proteomic profiles of centenarians from the SWISS100 cohort, identifying 583 differentially expressed proteins compared to younger and geriatric groups. Cross‐validation with the independent datasets NECS and the TAME consortium confirmed a robust aging signature, while fractional polynomial regressions revealed a specific ...
Flavien Delhaes +8 more
wiley +1 more source
Exploring microRNAs, One Cell at a Time. [PDF]
Noncoding RNAKreutz J, Mitić T, Caporali A.
europepmc +1 more source
Alcohol, Clinical and Experimental Research, Volume 50, Issue 2, February 2026.Using mice, we applied multi‐omics to compare liver and skeletal muscle after chronic alcohol consumption. The liver responded more strongly across genes, proteins, and metabolites, with a lowered PC:PE ratio. Muscle showed inflammation, extracellular matrix activation, impaired mitochondrial energetics, and an elevated PC:PE ratio. Lipidomics affected
Craig R. G. Willis +6 more
wiley +1 more source
401-Gene Signature of Myocardial Dysfunction in Human Heart Failure: A Transcriptomic Analysis. [PDF]
CureusEstes-Schmalzl KJ +2 more
europepmc +1 more source