Results 111 to 120 of about 1,057,597 (306)
CRISPR/dCas9-Based Systems: Mechanisms and Applications in Plant Sciences. [PDF]
Plants (Basel), 2021 Karlson CKS +3 more
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Position Vectors of General Helices According to Type-2 Bishop Frame in E^3 [PDF]
, 2018 In this paper, we study the position vector of a general helix according to type-2 Bishop frame in the3-dimensional Euclidean space E3.
Mahmut ERGÜT +5 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Academy of Sciences Proceedings Vol. 30-34
, 1953 periodicalFOUNDED April 3, 1908, the Utah Academy of Sciences was organized- to promote investigations and diffuse knowledge in all departments of science. In June 1933, at the annual meeting, the Academy was enlarged to include the arts and letters, and
Utah Academy of Sciences, Arts, and Letters
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Validation of Simulation: Patterns in the Social and Natural Sciences [PDF]
In most cases, the meaning of computer simulation is strongly connected to the idea numerical calculations. A computer simulation is a numerical solution of a complex mathematical problem.
G�nter K�ppers, Johannes Lenhard
core
Discrete-element modelling: methods and applications in the environmental sciences
, 2004 This paper introduces a Theme Issue on discrete-element modelling, based on research presented at an interdisciplinary workshop on this topic organized by the National Institute of Environmental e-Science. The purpose of the workshop, and this collection
Bithell, M. +7 more
core +1 more source
Algorithms in Tomography and Related Inverse Problems—A Review
AlgorithmsIn the ever-evolving landscape of tomographic imaging algorithms, this literature review explores a diverse array of themes shaping the field’s progress.
Styliani Tassiopoulou +2 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source