Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Some positive dependence notions, with applications in actuarial sciences. [PDF]
The paper is devoted to the study of several notions of positive dependence among risks, namely association, linear positive quadrant dependence, positive orthant dependence and conditional increasingness in sequence.
Denuit, M, Ribas, C, Dhaene, Jan
core
Experiences of Using Generative Communications to Support Adaptive Mobile Applications [PDF]
Attention has recently begun to focus on the use of asynchronous paradigms to support adaptive mobile applications. To investigate this issue the authors have developed an asynchronous distributed systems platform based on the tuple space paradigm ...
Friday, Adrian +8 more
core +1 more source
Lignin: Drug/Gene Delivery and Tissue Engineering Applications
Raj Kumar,1 Arun Butreddy,2 Nagavendra Kommineni,3 Pulikanti Guruprasad Reddy,4 Naveen Bunekar,5 Chandrani Sarkar,6 Sunil Dutt,7 Vivek K Mishra,8 Keshaw Ram Aadil,9 Yogendra Kumar Mishra,10 David Oupicky,1 Ajeet Kaushik11 1Center for Drug Delivery and ...
Kumar R +11 more
doaj
Temporal variations in the pattern of breathing: techniques, sources, and applications to translational sciences. [PDF]
Oku Y.
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Genetically encoded fluorescent probes : some properties and applications in the life sciences
The green fluorescent protein (GFP) was first isolated from the bell margin tissue of the bioluminescent jellyfish, Aequorea victoria. Some key advantages for using fluorescent protein (FP) technology are highlighted in Table 3.1.
Prescott, Mark, Salih, Anya (R12014)
core
Porphyrin-based electrospun nanomaterials for life science applications
Porphyrins are renowned for their utility in photocatalysis, electronics, sensors, solar cell dyes, and environmental remediation. However, their potential in life sciences applications remains underexplored, particularly in the context of encapsulation ...
Ana C. Mendes +4 more
doaj +1 more source
Mittag-Leffler Functions and Their Applications
Motivated essentially by the success of the applications of the Mittag-Leffler functions in many areas of science and engineering, the authors present, in a unified manner, a detailed account or rather a brief survey of the Mittag-Leffler function ...
H. J. Haubold +2 more
doaj +1 more source
THE IMPACT OF INFORMATION TECHNOLOGY UPON ECONOMIC SCIENCE
Rapid advances in information technology seem likely to change radically its usefulness for the economics profession. This paper reviews the range of existing applications and those that will probably emerge.
Paul A. David +1 more
doaj +1 more source

