Results 81 to 90 of about 1,057,597 (306)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

ABOUT THE BHOPAL SCHOOL OF SOCIAL SCIENCES (BSSS)

open access: yes, 2021
The Bhopal School of Social Sciences was founded in the year 1972-at the initiative of Most Rev Dr. Eugene D' Souza, the then Archbishop of Bhopal-in response to the need of the time for a broadbased, job-oriented curriculum with an initial focus on ...
The Bhopal School of Social Sciences
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Systems biology in animal sciences [PDF]

open access: yes, 2011
Systems biology is a rapidly expanding field of research and is applied in a number of biological disciplines. In animal sciences, omics approaches are increasingly used, yielding vast amounts of data, but systems biology approaches to extract ...
Pas, M.F.W., te   +11 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Spatial transformations: from fundamentals to applications [PDF]

open access: yes, 2015
We acknowledge the financial support of the Engineering and Physical Sciences Research Council (EPSRC), via the programme grant ‘The Quest for Ultimate Electromagnetics using Spatial Transformations (QUEST)’, grant no.
Grant, P   +5 more
core   +1 more source

Applications of Graphene and Graphene Oxide in Smart Drug/Gene Delivery: Is the World Still Flat?

open access: yesInternational Journal of Nanomedicine, 2020
Mojtaba Hoseini-Ghahfarokhi,1,2 Soroush Mirkiani,3 Naeimeh Mozaffari,4 Mohamad Amin Abdolahi Sadatlu,5 Amir Ghasemi,6,7 Somayeh Abbaspour,6 Mohsen Akbarian,8 Fatemeh Farjadain,8 Mahdi Karimi9 1Nano Drug Delivery Research Center, Kermanshah University of ...
Hoseini-Ghahfarokhi M   +8 more
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

How the Marsden Fund has failed to achieve its full potential in the ESA panel: evidence of limitations in scope, biased outcomes, and futile applications

open access: yes, 2014
We have analysed the scope of proposals funded by the ‘Earth Sciences and Astronomy’ (ESA) panel of the Marsden Fund for the period 2004 to 2013.
Lowe, David J., Bryan, Karin R.
core  

Home - About - Disclaimer - Privacy