Results 81 to 90 of about 169,669 (288)
, 2020 We present a compact two-lens high-density polyethylene (HDPE) f/1.6 refractor design that is capable of supporting a 28-deg diffraction-limited field of view at 1-mm wavelengths and contrast it to a similar two-lens refractor using silicon lenses.
Gudmundsson, Jon E.,
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Optical turbulence forecast in the Adaptive Optics realm
, 2018 Scientific drivers related to the optical turbulence forecast applied to the ground-based astronomy supported by Adaptive Optics, the state of the art of the achieved results and the most relevant challenges for future progresses are ...
TURCHI, ALESSIO +5 more
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
iScienceSummary: This paper presents a novel fiber-optic temperature sensor based on correlated color temperature (CCT) measurement. The sensor is formed by a homogeneous mixture of polydimethylsiloxane (PDMS) and cerium-doped yttrium aluminum garnet (YAG:Ce ...
Jan Jargus +5 more
doaj +1 more source
Transformation optics, isotropic chiral media and non-Riemannian geometry
, 2011 Copyright © 2011 IOP Publishing Ltd and Deutsche Physikalische GesellschaftOpen Access journalArticle published under a Creative Commons Attribution 3.0 Unported (CC-BY) licenseThe geometrical interpretation of electromagnetism in transparent media ...
Horsley, S. A. R. +2 more
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Beam shaping elements for single photon sources based on 3D printed micro-optics [PDF]
EPJ Web of ConferencesMultiple researchers have explored the use of 3D printed micro-optical components as interfaces to quantum point emitters by considering different designs and configurations. Typically, these designs involve parametric structures optimized in combination
Jimenez Carlos +2 more
doaj +1 more source
Swept source optical coherence tomography Gabor fusion splicing technique for microscopy of thick samples using a deformable mirror [PDF]
, 2015 We present a swept source optical coherence tomography (OCT) system at 1060 nm equipped with a wavefront sensor at 830 nm and a deformable mirror in a closed-loop adaptive optics (AO) system.
Adrian Bradu +9 more
core +1 more source