Results 91 to 100 of about 14,103,706 (328)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Optimization of Thermal Control Design for Aerial Reflective Opto-Mechanical Structure

open access: yesSensors
To improve the adaptability of aerial reflective opto-mechanical structures (mainly including the primary mirror and secondary mirror) to low-temperature environments, typically below −40 °C, an optimized thermal control design, which includes passive ...
Huilin Wang   +4 more
doaj   +1 more source

Imaging arbitrary incoherent source distributions with near quantum-limited resolution

open access: yesScientific Reports, 2022
We demonstrate an approach to obtaining near quantum-limited far-field imaging resolution of incoherent sources with arbitrary distributions. Our method assumes no prior knowledge of the source distribution, but rather uses an adaptive approach to ...
Erik F. Matlin, Lucas J. Zipp
doaj   +1 more source

Micro-machined membrane deformable mirrors for cryogenic adaptive optics [PDF]

open access: yes, 2002
In this Thesis, the suitability of 37 actuator Micro-machined membrane deformable mirrors (MMDM) for adaptive optics at cryogenic temperatures is evaluated. A method is described to safely cool MMDMs to 78K. The initial surface figures of three MMDMs are
Dyson, H.M., Dyson, Harold Michael
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

TechFix: Online Electronic Appliance Repairing Portal

open access: yes
<p><span>In today's digital age, the internet has transformed how we handle various tasks, making them<span> </span>more<span> </span>accessible,<span> </span>efficient,<span> </span>and time ...
JOURNAL OF APPLIED OPTICS
core   +1 more source

Optimising the NAOMI adaptive optics real-time control system [PDF]

open access: yes, 2008
This thesis describes the author's research in the field of Real-Time Control (RTC) for Adaptive Optics (AO) instrumentation. The research encompasses experiences and knowledge gained working in the area of RTC on astronomical instrumentation projects ...
Goodsell, S. J., Goodsell, S J
core  

Interferometric nulling of four channels with integrated optics

open access: yes, 2022
S.7449-7454Nulling interferometry has been identified as a competitive technique for the detection of extrasolar planets. In its basic form, the technique consists of combining out-of-phase a single pair of telescopes to effectively null the light of a ...
Pertsch, Thomas   +6 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Applied Optics

open access: yes, 2014
This feature issue serves as a pilot issue promoting the joint issue of Applied Optics and Chinese Optics Letters. It focuses upon topics of current relevance to the community working in the area of digital holography and 3-D imaging.
Poon, Ting-Chung
core   +1 more source

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