Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Conception and development of an adaptive optics testbed for free-space optical communication [PDF]
Optical free space communications are an efficient approach to transmit high data-rates with small antennas and low power consumption over large distances. Possible scenarios are links between satellites, up- and down-links from and to ground stations as
Moll, Florian
core
Summary: This paper presents a novel fiber-optic temperature sensor based on correlated color temperature (CCT) measurement. The sensor is formed by a homogeneous mixture of polydimethylsiloxane (PDMS) and cerium-doped yttrium aluminum garnet (YAG:Ce ...
Jan Jargus +5 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Extended optimization of chromatic aberrations via a hybrid Taguchi-genetic algorithm for zoom optics with a diffractive optical element [PDF]
[[abstract]]In this research, we propose a new method, a hybrid Taguchi–genetic algorithm (HTGA), for optics and zoom optics with a diffractive optical element (DOE) in order to eliminate chromatic aberration more efficiently than traditional damped ...
劉東官 +1 more
core +1 more source
Summary: We propose a time-domain adjoint optimization method for achromatic metalens design, achieving high efficiency and near-uniform spectral response.
Mingyu Park +2 more
doaj +1 more source
Beam shaping elements for single photon sources based on 3D printed micro-optics [PDF]
Multiple researchers have explored the use of 3D printed micro-optical components as interfaces to quantum point emitters by considering different designs and configurations. Typically, these designs involve parametric structures optimized in combination
Jimenez Carlos +2 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Swept source optical coherence tomography Gabor fusion splicing technique for microscopy of thick samples using a deformable mirror [PDF]
We present a swept source optical coherence tomography (OCT) system at 1060 nm equipped with a wavefront sensor at 830 nm and a deformable mirror in a closed-loop adaptive optics (AO) system.
Adrian Bradu +9 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source

