Results 71 to 80 of about 169,669 (288)

Applied Optics

open access: yes, 2014
This feature issue serves as a pilot issue promoting the joint issue of Applied Optics and Chinese Optics Letters. It focuses upon topics of current relevance to the community working in the area of digital holography and 3-D imaging.
Poon, Ting-Chung
core   +1 more source

Laser applications to chemical, security, and environmental analysis : introduction to the feature issue

open access: yes, 2021
This Applied Optics feature issue on laser applications to chemical, security, and environmental analysis (LACSEA) highlights papers presented at the LACSEA 2020 Seventeenth Topical Meeting sponsored by The Optical Society (OSA)
Seeger, Thomas,   +12 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Micro scanning mirrors and enabling technology for applied optics

open access: yes, 2022
Paper AIT4B.1Micro scanning mirrors play an important role in various optical applications for highly miniaturized, reliable and cost efficient scanning systems like compact laser projection displays, endoscopic and medical imaging systems or LIDAR 3D ...
Sandner, Thilo
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Physical Optics Applied to Parallel-Plate Lens Antennas

open access: yesIEEE Open Journal of Antennas and Propagation
The Physical Optics (PO) method is used to derive simplified expressions to compute the radiation electric fields of planar graded-index and geodesic lenses based on a parallel-plate waveguide (PPW) implementation.
Francisco Mesa   +3 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

System Design and Performance Characterization of a MEMS-Based Laser Scanning Time-of-Flight Sensor Based on a 256 $\times$ 64-pixel Single-Photon Imager

open access: yesIEEE Photonics Journal, 2013
This paper reports on a light detection and ranging (LIDAR) system that incorporates a microelectromechanical-system (MEMS) mirror scanner and a single-photon imager.
Kota Ito   +7 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Adaptive optics point spread function reconstruction directly from target data

open access: yes, 2016
Paper AOT2C.1, 3 S.Reconstruction of point spread function (PSF) using information from the wavefront sensor is a classic problem in adaptive optics. Although the theory and methods for this task have been in use for the last twenty years, implementation
Szymon Gladysz, Gladysz, Szymon
core   +1 more source

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