Results 141 to 150 of about 2,669,677 (322)

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Ga@MXene-based flexible wearable biosensor for glucose monitoring in sweat

iScience
Summary: Most wearable biosensors struggle to balance flexibility and conductivity in their sensing interfaces. In this study, we propose a wearable sensor featuring a highly stretchable, three-dimensional conductive network structure based on liquid ...
Wensi Zhang, Shuyue Jiang, Hongquan Yu, Shilun Feng, Kaihuan Zhang   +4 more
doaj  

Bibliotheca Chemico-Mathematica: A Catalogue of Works in many Tongues on Exact and Applied Science, with a Subject Index.

, 1922
Morris R. Cohen, H. Z., H. C. S.
openalex   +2 more sources

Applied Physical Sciences in the University of Reading: Prof. P. B. Fellgett [PDF]

, 1965
Farquharson Is Brown, Prof Gilliland, John D. Phillips, Martha W. Young, Dr Young, Mr Brewer   +5 more
openalex   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

“PyTDL”: A versatile temporal difference learning algorithm to simulate behavior process of decision making and cognitive learning

iScience
Summary: Humans and animals excel at learning complex tasks through reward-based feedback, dynamically adjusting value expectations and choices based on past experiences to optimize outcomes. However, understanding the hidden cognitive components driving
Qiyun Wu, Xiaodan Yang, Kaishu Wang, Min Zhu, Jiejunyi Liang, Yunyun Han   +5 more
doaj  

Second Chair of Applied Physical Sciences in the University of Reading [PDF]

, 1965

openalex   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Cutting-edge microneedle innovations: Transforming the landscape of cardiovascular and metabolic disease management

iScience
Summary: Cardiovascular diseases (CVDs) and metabolic disorders (MDs) have surfaced as formidable challenges to global health, significantly imperiling human well-being. Recently, microneedles (MNs) have garnered substantial interest within the realms of
Xiaoning Zhang, Ming Li, Qiang Gao, Xiaoya Kang, Jingyao Sun, Yao Huang, Hong Xu, Jing Xu, Songren Shu, Jian Zhuang, Yuan Huang   +10 more
doaj  

Institute of Applied Science, Victoria [PDF]

, 1965

openalex   +1 more source