Results 161 to 170 of about 11,399,306 (340)

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Cutting-edge microneedle innovations: Transforming the landscape of cardiovascular and metabolic disease management

iScience
Summary: Cardiovascular diseases (CVDs) and metabolic disorders (MDs) have surfaced as formidable challenges to global health, significantly imperiling human well-being. Recently, microneedles (MNs) have garnered substantial interest within the realms of
Xiaoning Zhang, Ming Li, Qiang Gao, Xiaoya Kang, Jingyao Sun, Yao Huang, Hong Xu, Jing Xu, Songren Shu, Jian Zhuang, Yuan Huang   +10 more
doaj  

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Dynamics of the oral microbiome during orthodontic treatment and antimicrobial advances for orthodontic appliances

iScience
Summary: The oral microbiome plays an important role in human health, and an imbalance of the oral microbiome could lead to oral and systemic diseases. Orthodontic treatment is an effective method to correct malocclusion.
Qin Niu, Si Chen, Rushui Bai, Yuntao Lu, Liying Peng, Bing Han, Tingting Yu   +6 more
doaj  

The graduation shift of German universities of applied sciences. [PDF]

PLoS One, 2019
Bornmann L, Wohlrabe K, Gralka S.
europepmc   +1 more source

Book reviewsConcrete structures: repair, waterproofing and protection PerkinsPhilip H. Published by Applied Science Publishers Ltd, London, 1976. Type-set, illustrated, hard-back. 238 × 148 mm. pp. x, 302. ISBN 0 85334 697 6. Price: £16.00. [PDF]

, 1977
Roy Galbraith
openalex   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Roles and therapeutic opportunities of ω-3 long-chain polyunsaturated fatty acids in lung cancer

iScience
Summary: Over the past decades, researchers have continuously investigated the potential functions of long-chain polyunsaturated fatty acids (LCPUFAs) in cancers, including lung cancer.
Jiang Luo, Shu Peng, Ziyu Jiang, Qingwei Wang, Mini Zhang, Yuxin Zeng, Yu Yuan, Min Xia, Zixi Hong, Yufei Yan, Yushuang Tan, Jiawen Tang, Conghua Xie, Yan Gong   +13 more
doaj  

Recent Advances in Liquid Chromatography-Mass Spectrometry (LC-MS) Applications in Biological and Applied Sciences. [PDF]

Anal Sci Adv
Alanazi S.
europepmc   +1 more source

The Bimini installation to U.S. Department of the Navy, Office of Naval Research, Biology Branch, Contract Nonr 840 (13). Accoustics Branch, Contract Nonr 840 (16). Bureau of Ships, Applied Sciences Branch, Contract Nobs 84540; Sonar Branch, Bell Telephone Laboratories purchase order, D-602526, based on Prime Contract Nobsr 57093

, 1961

openalex   +2 more sources