Results 171 to 180 of about 11,399,306 (340)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Computer-aided robotics for applications in fracture reduction surgery: Advances, challenges, and opportunities

iScience
Summary: The advancement of information technology and AI has boosted global economic and social development. Robot systems (RS) and computer-aided technology (CAT) are used in various domains, including social production and human existence. Traditional
Xianzheng Zhou, Yimiao Chen, Genyuan Miao, Yanchao Guo, Qinhe Zhang, Jianping Bi   +5 more
doaj  

Body Appreciation, Weight Status, and Weight Management Practices Among First-Year Students at Universities of Applied Sciences in Lithuania. [PDF]

Medicina (Kaunas)
Kriaučionienė V, Raskilienė A, Šnipaitienė L, Petkevičienė J.   +3 more
europepmc   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Laser-induced voltage of table salt for deep ultraviolet pulsed laser detection

iScience
Summary: To meet the requirements of fast response and simple process of deep ultraviolet (UV) pulsed laser detector, table salt (TS) was used as laser detection material in combination with a variable resistor to achieve single-pulse laser detection ...
Xuecong Liu, Kun Zhao, Xinyang Miao
doaj  

The quagga mussel, Dreissena rostriformis: a novel model for EcoEvoDevo, environmental research, and the applied sciences. [PDF]

Front Cell Dev Biol
Wanninger A, Schwarze G.
europepmc   +1 more source

Natural and Applied Sciences [PDF]

, 1974
Donald, Emmanuele Farris, James Μ. McGrann, James R. Simpson, Ray Billingsley, Clive Harston, Pedro Sanchez, S. W. Buol, E. J. Kamprath, D Oelsligle, G. C. Naderman, Aristides Giavelli, Andres Scherson   +12 more
openalex   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

A human-system integration framework and its application for special vehicle interface design under typical human readiness levels

iScience
Summary: Life cycle Human System Integration (HSI) practices are crucial for optimizing human system performance, reducing costs, and ensuring safety. To address the limited HSI practices under typical Human Readiness Levels (HRLs), our study proposes an
Chuanyan Feng, Shuang Liu, Xiaoru Wanyan, Zhenjia Sun, Fang Xie   +4 more
doaj