Results 81 to 90 of about 6,938,619 (347)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Fitness or socializing - A multi-dimensional analysis of online fitness communities users

iScience
Summary: The digital and social network revolution in the fitness industry will provide consumers with opportunities to achieve their healthy and active lifestyle goals both online and offline.
Lei Wang, Wanxuan Feng, Jianghua Zhang, Tuojian Li   +3 more
doaj   +1 more source

EVALUATION REPORT OF LAUREA UNIVERSITY OF APPLIED SCIENCES 2010 [PDF]

, 2011
In this report, the evaluation board considers international level RDI and a high quality research culture as a central means for attaining Laurea’s vision.
Löytönen, Markku, Schwab-Matkovits, Ingrid, Spaapen, Jack, Varmola, Tapio   +3 more
core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Advances in nanoparticle-based radiotherapy for cancer treatment

iScience
Summary: Radiotherapy has long been recognized as an effective conventional approach in both clinical and scientific research, primarily through mechanisms involving DNA destruction or the generation of reactive oxygen species to target tumors.
Meijuan He, Shixiong Chen, Hongwei Yu, Xuhui Fan, Hong Wu, Yihui Wang, Han Wang, Xiaorui Yin   +7 more
doaj   +1 more source

Eurasian Journal of Law, Finance and Applied Sciences

, 2023
Миркомил Камилов, Миркомил Камилов   +1 more
openalex   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Basin dependencies of tropical cyclone genesis environment and possible future changes revealed by machine learning methods

iScience
Summary: Tropical cyclone (TC) genesis mechanisms remain debated, complicating predictions of climate change impacts. This study uses principal-component analysis (PCA), confidence ellipses, and correlation circles to analyze TC genesis environments ...
QiFeng Qian, YeFeng Chen, XiaoJing Jia, Hao Ma, Wei Dong   +4 more
doaj   +1 more source

Open Science in Applied Linguistics: An Introduction to Metascience

, 2023
Ali H. Al‐Hoorie, Phil Hiver
openalex   +2 more sources

Reactor monitoring and safeguards using antineutrino detectors

, 2008
Nuclear reactors have served as the antineutrino source for many fundamental physics experiments. The techniques developed by these experiments make it possible to use these very weakly interacting particles for a practical purpose.
Applied Antineutrino Physics, Applied Antineutrino Physics, Ardellier F, Bowden N S, Collar J, Dazeley S, Fallot M, Guillian E, Mention G, Mikaelian L A, Monteith A, N S Bowden, Neutrino Sciences, Neutrinos, Porta A, Sinev V, Suekane F   +16 more
core   +1 more source