Results 81 to 90 of about 4,634,807 (256)
, 2016 We propose new summary statistics to quantify the association between the components in coverage-reweighted moment stationary multivariate random sets and measures.
van Lieshout, M. N. M.
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Statistics applied to plant micropropagation: a critical review of inadequate use
Bioscience Journal, 2018 Statistical analyses are an essential part of scientific research. Various procedures since the preparation of the experiment have an impact on the statistical procedures adopted. Therefore, a correct planning implies a precise analysis.
Vanderley José Pereira +4 more
doaj +3 more sources
Journal of the Royal Statistical Society Series C: Applied Statistics, 2020 N. Friel +21 more
openaire +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Special section on modern multivariate analysis
, 2012 A critically challenging problem facing statisticians is the identification of a suitable framework which consolidates data of various types, from different sources, and across different time frames or scales (many of which can be missing), and from ...
Kafadar, Karen
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
On the nonextensive character of some magnetic systems
, 2007 During the past few years, nonextensive statistics has been successfully applied to explain many different kinds of systems. Through these studies some interpretations of the entropic parameter q, which has major role in this statistics, in terms of ...
Andrea Rapisarda +8 more
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source