Results 41 to 50 of about 130,322 (292)

Appointment Scheduling at Outpatient Clinics Using Two-Stage Stochastic Programming Approach

open access: yesIEEE Access, 2020
Clinics with a large volume of patients are often burdened with limited resources such as nurses and providers. Also, an efficient health system seeks short wait times for the patients to see the provider (indirect wait time) and within the clinic ...
Samira Fazel Anvaryazdi   +2 more
doaj   +1 more source

Clocks in Dreams: Analysis of a Long Dream Series

open access: yesClocks & Sleep, 2021
Many dream content analytic studies focus on dream characters, animals, social interactions and so on, but they rarely analyze the frequency of everyday objects in dreams.
Michael Schredl
doaj   +1 more source

Campus Concierge: A Business Plan to Do College Better [PDF]

open access: yes, 2016
Campus Concierge Inc. is a start-up company located in Fayetteville, Arkansas that provides academic support services to college students. Since 2013, the company has seen successful operations and is ready to expand.
Birch, Hannah G
core   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

The effect of scheduled visits on delirium intensity in elderly patients hospitalized in the Intensive Care Unit: a clinical trial study

open access: yesحیات, 2019
Background & Aim: Active participation of families can be an influencing factor on delirium in patients hospitalized in the ICU. The present study was conducted to investigate the effect of scheduled visits on delirium intensity in elderly patients ...
Ali Hasanshahian   +2 more
doaj  

Impact of value added services on patient waiting time at the ambulatory pharmacy Queen Elizabeth Hospital

open access: yesPharmacy Practice, 2017
Background: Value added services (VAS) are an innovative dispensing system created to provide an alternative means of collecting partial drug supply from our hospital.
Loh BC   +5 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Access to general practice during the COVID-19 pandemic - a cross-sectional view of the opinions of adults who use social media

open access: yesRural and Remote Health, 2023
Introduction: The COVID-19 pandemic has had a significant impact on the health and wellbeing of people worldwide. General practices were forced to adapt to constantly changing circumstances, leading to predominance of virtual consultations.
Gabriela Mineva   +8 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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