Results 111 to 120 of about 1,127,076 (293)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Likelihood neglect bias and the mental simulations approach: An illustration using the old and new Monty Hall problems

Judgment and Decision Making
This article introduces a new violation of a law of probability, likelihood neglect bias. The bias occurs when one is (i) aware that some evidence is more likely given one hypothesis rather than another but (ii) that evidence does not cause them to raise
John E. Wilcox
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

ALICE Measurements in p-Pb Collisions: Charged Particle Multiplicity, Centrality Determination and implications for Binary Scaling

, 2014
Measurements of particle production in proton-nucleus collisions provide a reference to disentangle final state effects, i.e. signatures of the formation of a deconfined hot medium, from initial state effects, already present in cold nuclear matter ...
Toia, Alberica
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Negative effects of an alternating-bias training aimed at attentional flexibility: a single session study

Health Psychology and Behavioral Medicine, 2017
Attentional Bias Modification (ABM) usually aims to induce automatic biases directed toward or away from certain stimulus categories. An alternative approach, termed Attention Control Training (ACT), uses a similar paradigm but aims to train the ability ...
Thomas E. Gladwin
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Has saturation physics been observed in deuteron-gold collisions at RHIC?

, 2005
In the framework of the recently proposed saturation picture, we examine in a systematic way whether the nuclear modification factor measured for d-Au collisions at RHIC may be simply explained.
Accardi, Adams, Adcox, Adler, Albacete, Arleo, Arsene, Arsene, Aurenche, Aversa, Back, Baier, Baier, Baier, Baier, Balitsky, Balitsky, Bethe, Blaizot, Blaizot, de Florian, Debbe, Dominique Schiff, Dumitru, Dumitru, Fontannaz, Gaardhoje, Gelis, Gluck, Guzey, Iancu, Iancu, Iancu, Iancu, Jalilian-Marian, Jalilian-Marian, Jäger, Kharzeev, Kharzeev, Kharzeev, Kharzeev, Kharzeev, Kniehl, Kovchegov, Kovchegov, Kovchegov, Kuraev, Mueller, Munier, Munier, Rudolf Baier, Yacine Mehtar-Tani   +51 more
core   +4 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Machine Learning Approach to Predict the DC Bias for Adaptive OFDM Transmission in Indoor Li-Fi Applications

IEEE Access
Multilevel quadrature amplitude modulation (M-QAM) combined with DC-bias in optical orthogonal frequency division multiplexing (DCO-OFDM) offers a spectrally efficient solution and adaptive transmission rates for indoor light-fidelity (Li-Fi) systems ...
Marwah T. Salman, David R. Siddle, Amadi G. Udu   +2 more
doaj   +1 more source