Results 31 to 40 of about 14,107 (216)
International Journal of Advanced Robotic Systems, 2020 The problem of optimal tracking control for robot–environment interaction is studied in this article. The environment is regarded as a linear system and an admittance control with iterative linear quadratic regulator method is obtained to guarantee the ...
Hong Zhan +4 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
IEEE Access, 2018 In this paper, the approximate dynamic programming (ADP) technique is used to resolve the cooperative control problem for the completely model-free linear multi-agent systems in both continuoustime and discrete-time cases.
Yanhua Qu, Anna Wang, Jinglu Liu
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IEEE Access, 2021 A data-driven approximation formulation for the state reconstruction problem of dynamical systems is presented in this paper. Without the assumption of an explicit mathematical model, the Hamilton–Jacobi–Bellman (HJB) based approach of a ...
Fabio Nogueira Da Silva +1 more
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Reservoir optimization and machine learning methods
EURO Journal on Computational Optimization, 2023 Optimization of storage using neural networks is now commonly achieved by solving a single optimization problem. We first show that this approach allows solving high-dimensional storage problems, but is limited by memory issues. We propose a modification
Xavier Warin
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
A Fast and Optimal Smart Home Energy Management System: State-Space Approximate Dynamic Programming
IEEE Access, 2020 Dynamic programming (DP) can be used to generate the optimal schedules of a smart home energy management system (SHEMS), however, it is computationally difficult because we have to loop over all the possible states, decisions and outcomes.
Zhiheng Zhao, Chanaka Keerthisinghe
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