Results 1 to 10 of about 231,944 (161)

Post-treatment with H12-(ADP)-liposomes after LPS challenge ameliorated coagulopathy and critical organ injury in rats [PDF]

open access: yesIntensive Care Medicine Experimental
Background Liposomes coated with fibrinogen γ-chain (HHLGGAKQAGDV, H12) peptide and encapsulating adenosine-diphosphate (ADP) [H12-(ADP)-liposomes] can augment platelet aggregation via glycoprotein IIb/IIIa receptors displayed on activated platelets. H12-
Kohsuke Hagisawa   +5 more
doaj   +2 more sources

Versatile and sensitive detection of mono- and poly(ADP-ribosyl)ation reveals XRCC1-dependent remodelling of PARP1 signalling [PDF]

open access: yesNature Communications
ADP-ribosylation has long been recognised as a key regulator of essential signalling pathways, including the DNA damage response. However, only recent and ongoing technological advances are beginning to make it possible to investigate its distinct forms ...
Helen Dauben   +6 more
doaj   +2 more sources

ADP-Ribosyltransferases and Poly ADP-Ribosylation [PDF]

open access: yesCurrent Protein & Peptide Science, 2015
Protein ADP-ribosylation is an important posttranslational modification that plays versatile roles in multiple biological processes. ADP-ribosylation is catalyzed by a group of enzymes known as ADP-ribosyltransferases (ARTs). Using nicotinamide adenine dinucleotide (NAD(+)) as the donor, ARTs covalently link single or multiple ADP-ribose moieties from ...
Chao, Liu, Xiaochun, Yu
openaire   +2 more sources

POTENTIAL OF ALOE VERA GEL AS AN ALTERNATIVE INDUCTOR IN PLATELET AGGREGATION TEST

open access: yesJurnal Teknologi Laboratorium, 2023
Platelet aggregation test is important in evaluation platelet function. Inductors are substances that stimulate the aggregation process. The use of ADP (adenosine diphosphate as an inductor has the disadvantage of being costly and difficult to obtain ...
Gela Setya Ayu Putri, Andri Sukeksi
doaj   +1 more source

Implementing the RDA Research Data Policy Framework in Slovenian Scientific Journals

open access: yesData Science Journal, 2020
The paper aims to present the implementation of the RDA research data policy framework in Slovenian scientific journals within the project RDA Node Slovenia.
Janez Štebe   +3 more
doaj   +1 more source

ADP and Thromboxane Inhibitors Both Reduce Global Contraction of Clot Length, While Thromboxane Inhibition Attenuates Internal Aggregate Contraction

open access: yesTH Open, 2022
Platelet contractility drives clot contraction to enhance clot density and stability. Clot contraction is typically studied under static conditions, with fewer studies of wall-adherent platelet clots formed under flow.
Kevin T. Trigani   +2 more
doaj   +1 more source

PROBLEMS OF DIGITALIZATION OF THE RUSSIAN INDUSTRY

open access: yesСтратегические решения и риск-менеджмент, 2022
The article is devoted to the substantiation of the model of the formation of an industrial development ecosystem based on modern digital technologies in industry.The article deals with the problems of technological sovereignty of the Russian economy. It
Y. S. Bogachev   +2 more
doaj   +1 more source

The Relationship Between Premature Adrenarche and Platelet Aggregation

open access: yesJCRPE, 2023
INTRODUCTION: Premature adrenarche (PA) has been associated with an increase in adrenal androgens, and the hyperandrogenic hormonal environment is known to lead to increased platelet (PLT) aggregation.
Ahmet Bolat   +4 more
doaj   +1 more source

The effect of chlorin e6 drug on platelet aggregation activity

open access: yesBiomedical Photonics, 2019
The goal of the study is to evaluate the effect of Radachlorin (OOO “RADA-PHARMA”, Russia) (RC) on platelet aggregation in ex vivo and in vivo experiments. The experiments were conducted on male Wistar rats.
N. N. Petrishchev   +4 more
doaj   +1 more source

Antiplatelet activity of deferiprone through cyclooxygenase-1 inhibition

open access: yesPlatelets, 2020
Thalassemia patients are susceptible to both iron overload and thromboembolism. Deferiprone is an iron chelator that shows an antiplatelet activity and thus may alleviate platelet hyperactivation in thalassemia.
Ngan Thi Tran   +4 more
doaj   +1 more source

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